Cargando…
Improving the Treatment of Acute Lymphoblastic Leukemia
[Image: see text] l-Asparaginase (EC 3.5.1.1) was first used as a component of combination drug therapies to treat acute lymphoblastic leukemia (ALL), a cancer of the blood and bone marrow, almost 50 years ago. Administering this enzyme to reduce asparagine levels in the blood is a cornerstone of mo...
Autores principales: | Radadiya, Ashish, Zhu, Wen, Coricello, Adriana, Alcaro, Stefano, Richards, Nigel G. J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497903/ https://www.ncbi.nlm.nih.gov/pubmed/32786406 http://dx.doi.org/10.1021/acs.biochem.0c00354 |
Ejemplares similares
-
Cryo-EM and Molecular Dynamics Simulations Reveal Hidden Conformational Dynamics Controlling Ammonia Transport in Human Asparagine Synthetase
por: Coricello, Adriana, et al.
Publicado: (2023) -
Inside Perspective of the Synthetic and Computational Toolbox of JAK Inhibitors: Recent Updates
por: Coricello, Adriana, et al.
Publicado: (2020) -
Acute lymphoblastic leukemia
por: Schrappe, Martin
Publicado: (2018) -
Inotuzumab ozogamicin for the treatment of acute lymphoblastic leukemia
por: Savoy, J. Michael, et al.
Publicado: (2018) -
Venetoclax for Children and Adolescents with Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma
por: Gibson, Amber, et al.
Publicado: (2021)