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Characterization of an inorganic scintillator for small‐field dosimetry in MR‐guided radiotherapy
INTRODUCTION: Aim of this study is to dosimetrically characterize a new inorganic scintillator designed for magnetic resonance‐guided radiotherapy (MRgRT) in the presence of 0.35 tesla magnetic field (B). METHODS: The detector was characterized in terms of signal to noise ratio (SNR), reproducibilit...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497936/ https://www.ncbi.nlm.nih.gov/pubmed/32841500 http://dx.doi.org/10.1002/acm2.13012 |
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author | Cusumano, Davide Placidi, Lorenzo D'Agostino, Emiliano Boldrini, Luca Menna, Sebastiano Valentini, Vincenzo De Spirito, Marco Azario, Luigi |
author_facet | Cusumano, Davide Placidi, Lorenzo D'Agostino, Emiliano Boldrini, Luca Menna, Sebastiano Valentini, Vincenzo De Spirito, Marco Azario, Luigi |
author_sort | Cusumano, Davide |
collection | PubMed |
description | INTRODUCTION: Aim of this study is to dosimetrically characterize a new inorganic scintillator designed for magnetic resonance‐guided radiotherapy (MRgRT) in the presence of 0.35 tesla magnetic field (B). METHODS: The detector was characterized in terms of signal to noise ratio (SNR), reproducibility, dose linearity, angular response, and dependence by energy, field size, and B orientation using a 6 MV magnetic resonance (MR)‐Linac and a water tank. Field size dependence was investigated by measuring the output factor (OF) at 1.5 cm. The results were compared with those measured using other detectors (ion chamber and synthetic diamond) and those calculated using a Monte Carlo (MC) algorithm. Energy dependence was investigated by acquiring a percentage depth dose (PDD) curve at two field sizes (3.32 × 3.32 and 9.96 × 9.96 cm(2)) and repeating the OF measurements at 5 and 10 cm depths. RESULTS: The mean SNR was 116.3 ± 0.6. Detector repeatability was within 1%, angular dependence was <2% and its response variation based on the orientation with respect to the B lines was <1%. The detector has a temporal resolution of 10 Hz and it showed a linear response (R(2) = 1) in the dose range investigated. All the OF values measured at 1.5 cm depth using the scintillator are in accordance within 1% with those measured with other detectors and are calculated using the MC algorithm. PDD values are in accordance with MC algorithm only for 3.32 × 3.32 cm(2) field. Numerical models can be applied to compensate for energy dependence in case of larger fields. CONCLUSION: The inorganic scintillator in the present form can represent a valuable detector for small‐field dosimetry and periodic quality controls at MR‐Linacs such as dose stability, OFs, and dose linearity. In particular, the detector can be effectively used for small‐field dosimetry at 1.5 cm depth and for PDD measurements if the field dimension of 3.32 × 3.32 cm(2) is not exceeded. |
format | Online Article Text |
id | pubmed-7497936 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-74979362020-09-25 Characterization of an inorganic scintillator for small‐field dosimetry in MR‐guided radiotherapy Cusumano, Davide Placidi, Lorenzo D'Agostino, Emiliano Boldrini, Luca Menna, Sebastiano Valentini, Vincenzo De Spirito, Marco Azario, Luigi J Appl Clin Med Phys Radiation Measurements INTRODUCTION: Aim of this study is to dosimetrically characterize a new inorganic scintillator designed for magnetic resonance‐guided radiotherapy (MRgRT) in the presence of 0.35 tesla magnetic field (B). METHODS: The detector was characterized in terms of signal to noise ratio (SNR), reproducibility, dose linearity, angular response, and dependence by energy, field size, and B orientation using a 6 MV magnetic resonance (MR)‐Linac and a water tank. Field size dependence was investigated by measuring the output factor (OF) at 1.5 cm. The results were compared with those measured using other detectors (ion chamber and synthetic diamond) and those calculated using a Monte Carlo (MC) algorithm. Energy dependence was investigated by acquiring a percentage depth dose (PDD) curve at two field sizes (3.32 × 3.32 and 9.96 × 9.96 cm(2)) and repeating the OF measurements at 5 and 10 cm depths. RESULTS: The mean SNR was 116.3 ± 0.6. Detector repeatability was within 1%, angular dependence was <2% and its response variation based on the orientation with respect to the B lines was <1%. The detector has a temporal resolution of 10 Hz and it showed a linear response (R(2) = 1) in the dose range investigated. All the OF values measured at 1.5 cm depth using the scintillator are in accordance within 1% with those measured with other detectors and are calculated using the MC algorithm. PDD values are in accordance with MC algorithm only for 3.32 × 3.32 cm(2) field. Numerical models can be applied to compensate for energy dependence in case of larger fields. CONCLUSION: The inorganic scintillator in the present form can represent a valuable detector for small‐field dosimetry and periodic quality controls at MR‐Linacs such as dose stability, OFs, and dose linearity. In particular, the detector can be effectively used for small‐field dosimetry at 1.5 cm depth and for PDD measurements if the field dimension of 3.32 × 3.32 cm(2) is not exceeded. John Wiley and Sons Inc. 2020-08-25 /pmc/articles/PMC7497936/ /pubmed/32841500 http://dx.doi.org/10.1002/acm2.13012 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Measurements Cusumano, Davide Placidi, Lorenzo D'Agostino, Emiliano Boldrini, Luca Menna, Sebastiano Valentini, Vincenzo De Spirito, Marco Azario, Luigi Characterization of an inorganic scintillator for small‐field dosimetry in MR‐guided radiotherapy |
title | Characterization of an inorganic scintillator for small‐field dosimetry in MR‐guided radiotherapy |
title_full | Characterization of an inorganic scintillator for small‐field dosimetry in MR‐guided radiotherapy |
title_fullStr | Characterization of an inorganic scintillator for small‐field dosimetry in MR‐guided radiotherapy |
title_full_unstemmed | Characterization of an inorganic scintillator for small‐field dosimetry in MR‐guided radiotherapy |
title_short | Characterization of an inorganic scintillator for small‐field dosimetry in MR‐guided radiotherapy |
title_sort | characterization of an inorganic scintillator for small‐field dosimetry in mr‐guided radiotherapy |
topic | Radiation Measurements |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497936/ https://www.ncbi.nlm.nih.gov/pubmed/32841500 http://dx.doi.org/10.1002/acm2.13012 |
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