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Association of sleep quality and sleep duration with serum uric acid levels in adults
OBJECTIVE: To date, the association between sleep duration or sleep quality and hyperuricemia has remained unclear. In addition, sleep duration and quality were not considered concomitantly in previous studies. Thus, this study was aimed toward an examination of the association of sleep duration and...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497980/ https://www.ncbi.nlm.nih.gov/pubmed/32941519 http://dx.doi.org/10.1371/journal.pone.0239185 |
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author | Chou, Yu-Tsung Li, Chung-Hao Shen, Wei-Chen Yang, Yi-Ching Lu, Feng-Hwa Wu, Jin-Shang Chang, Chih-Jen |
author_facet | Chou, Yu-Tsung Li, Chung-Hao Shen, Wei-Chen Yang, Yi-Ching Lu, Feng-Hwa Wu, Jin-Shang Chang, Chih-Jen |
author_sort | Chou, Yu-Tsung |
collection | PubMed |
description | OBJECTIVE: To date, the association between sleep duration or sleep quality and hyperuricemia has remained unclear. In addition, sleep duration and quality were not considered concomitantly in previous studies. Thus, this study was aimed toward an examination of the association of sleep duration and quality with uric acid level in a Taiwanese population. METHODS: A total of 4,555 patients aged ≥18 years were enrolled in this study. The sleep duration was classified into three groups: short (<7 h), normal (7–9 h), and long (≥9 h). The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep quality, and poor sleep quality was defined as a global PSQI score of >5. RESULTS: Poor sleepers were younger and had lower body mass index, blood pressure, uric acid, blood sugar, cholesterol, creatinine level, shorter sleep duration, and engaged in less exercise but had a higher white blood cell count and prevalence of smoking as compared to good sleepers. There were also differences in body mass index, blood pressure, uric acid, blood sugar, lipid profiles, and sleep quality among subjects with different sleep durations. After adjusting for other variables, poor sleep quality was associated with lower uric acid levels. In addition, short sleep duration was positively associated with higher uric acid levels. CONCLUSIONS: Poor sleep quality was related to lower uric acid levels, whereas short sleep duration was associated with higher uric acid levels. |
format | Online Article Text |
id | pubmed-7497980 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-74979802020-09-24 Association of sleep quality and sleep duration with serum uric acid levels in adults Chou, Yu-Tsung Li, Chung-Hao Shen, Wei-Chen Yang, Yi-Ching Lu, Feng-Hwa Wu, Jin-Shang Chang, Chih-Jen PLoS One Research Article OBJECTIVE: To date, the association between sleep duration or sleep quality and hyperuricemia has remained unclear. In addition, sleep duration and quality were not considered concomitantly in previous studies. Thus, this study was aimed toward an examination of the association of sleep duration and quality with uric acid level in a Taiwanese population. METHODS: A total of 4,555 patients aged ≥18 years were enrolled in this study. The sleep duration was classified into three groups: short (<7 h), normal (7–9 h), and long (≥9 h). The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep quality, and poor sleep quality was defined as a global PSQI score of >5. RESULTS: Poor sleepers were younger and had lower body mass index, blood pressure, uric acid, blood sugar, cholesterol, creatinine level, shorter sleep duration, and engaged in less exercise but had a higher white blood cell count and prevalence of smoking as compared to good sleepers. There were also differences in body mass index, blood pressure, uric acid, blood sugar, lipid profiles, and sleep quality among subjects with different sleep durations. After adjusting for other variables, poor sleep quality was associated with lower uric acid levels. In addition, short sleep duration was positively associated with higher uric acid levels. CONCLUSIONS: Poor sleep quality was related to lower uric acid levels, whereas short sleep duration was associated with higher uric acid levels. Public Library of Science 2020-09-17 /pmc/articles/PMC7497980/ /pubmed/32941519 http://dx.doi.org/10.1371/journal.pone.0239185 Text en © 2020 Chou et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Chou, Yu-Tsung Li, Chung-Hao Shen, Wei-Chen Yang, Yi-Ching Lu, Feng-Hwa Wu, Jin-Shang Chang, Chih-Jen Association of sleep quality and sleep duration with serum uric acid levels in adults |
title | Association of sleep quality and sleep duration with serum uric acid levels in adults |
title_full | Association of sleep quality and sleep duration with serum uric acid levels in adults |
title_fullStr | Association of sleep quality and sleep duration with serum uric acid levels in adults |
title_full_unstemmed | Association of sleep quality and sleep duration with serum uric acid levels in adults |
title_short | Association of sleep quality and sleep duration with serum uric acid levels in adults |
title_sort | association of sleep quality and sleep duration with serum uric acid levels in adults |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497980/ https://www.ncbi.nlm.nih.gov/pubmed/32941519 http://dx.doi.org/10.1371/journal.pone.0239185 |
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