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Porphyromonas gingivalis promotes progression of esophageal squamous cell cancer via TGFβ-dependent Smad/YAP/TAZ signaling

Microbial dysbiosis in the upper digestive tract is linked to an increased risk of esophageal squamous cell carcinoma (ESCC). Overabundance of Porphyromonas gingivalis is associated with shorter survival of ESCC patients. We investigated the molecular mechanisms driving aggressive progression of ESC...

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Detalles Bibliográficos
Autores principales: Qi, Yi-Jun, Jiao, Ye-Lin, Chen, Pan, Kong, Jin-Yu, Gu, Bian-Li, Liu, Ke, Feng, Dan-Dan, Zhu, Ya-Fei, Ruan, Hao-Jie, Lan, Zi-Jun, Liu, Qi-Wei, Mi, You-Jia, Guo, Xiang-Qian, Wang, Ming, Liang, Gao-Feng, Lamont, Richard J., Wang, Huizhi, Zhou, Fu-You, Feng, Xiao-Shan, Gao, She-Gan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498034/
https://www.ncbi.nlm.nih.gov/pubmed/32886690
http://dx.doi.org/10.1371/journal.pbio.3000825