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Panorama de las carbapenemasas en Perú
OBJECTIVE. To describe the genotypes of the carbapenemases reported from microbiological isolates of patients in Peru. METHODS. A systematic search of the biomedical literature about carbapenemases with genotypic confirmation was carried out. It included literature published from 1 January 2000 thro...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Organización Panamericana de la Salud
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498286/ https://www.ncbi.nlm.nih.gov/pubmed/32973907 http://dx.doi.org/10.26633/RPSP.2020.61 |
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author | Angles-Yanqui, Eddie Huaringa-Marcelo, Jorge Sacsaquispe-Contreras, Rosa Pampa-Espinoza, Luis |
author_facet | Angles-Yanqui, Eddie Huaringa-Marcelo, Jorge Sacsaquispe-Contreras, Rosa Pampa-Espinoza, Luis |
author_sort | Angles-Yanqui, Eddie |
collection | PubMed |
description | OBJECTIVE. To describe the genotypes of the carbapenemases reported from microbiological isolates of patients in Peru. METHODS. A systematic search of the biomedical literature about carbapenemases with genotypic confirmation was carried out. It included literature published from 1 January 2000 through 15 September 2019 in the PubMed, SCOPUS, Virtual Health Library, CONCYTEC Virtual Library, and Google Scholar databases, and other sources for the publication of abstracts or posters from national or international meetings. Two reviewers carried out the data selection and extraction. RESULTS. Fourteen studies, which carried out the genotypic characterization of 313 carbapenemases, were included. Of the total 313 reports, 103 analyzed enterobacteria: 74 were of Klebsiella pneumoniae, 11 of Proteus mirabilis, 7 of Enterobacter cloacae, and 11 of other enterobacteria; and 61 corresponded to bla(NDM), 39 to bla(KPC,) and 3 to bla(IMP). According to their molecular structure, 64 were metallo-ß-lactamases and 39 were serine-ß-lactamases. Of the total reports, 84 analyzed Pseudomonas aeruginosa: 79 corresponded to bla(IMP), 4 to bla(VIM), and 1 to bla(GES.) Of the total reports, 126 analyzed Acinetobacter baumannii: 55 corresponded to bla(OXA-23), 66 to bla(OXA-24), 3 to bla(NDM,) and 2 to bla(OXA-143). CONCLUSIONS. There is a limited number of publications about carbapenemases among patients in Peru. The genotype reports come primarily from hospitals in the country’s capital. This is the first review that aims to identify the types of carbapenemases reported in enterobacteria, P. aeruginosa, and A. baummani. |
format | Online Article Text |
id | pubmed-7498286 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Organización Panamericana de la Salud |
record_format | MEDLINE/PubMed |
spelling | pubmed-74982862020-09-23 Panorama de las carbapenemasas en Perú Angles-Yanqui, Eddie Huaringa-Marcelo, Jorge Sacsaquispe-Contreras, Rosa Pampa-Espinoza, Luis Rev Panam Salud Publica Revisión Sistemática OBJECTIVE. To describe the genotypes of the carbapenemases reported from microbiological isolates of patients in Peru. METHODS. A systematic search of the biomedical literature about carbapenemases with genotypic confirmation was carried out. It included literature published from 1 January 2000 through 15 September 2019 in the PubMed, SCOPUS, Virtual Health Library, CONCYTEC Virtual Library, and Google Scholar databases, and other sources for the publication of abstracts or posters from national or international meetings. Two reviewers carried out the data selection and extraction. RESULTS. Fourteen studies, which carried out the genotypic characterization of 313 carbapenemases, were included. Of the total 313 reports, 103 analyzed enterobacteria: 74 were of Klebsiella pneumoniae, 11 of Proteus mirabilis, 7 of Enterobacter cloacae, and 11 of other enterobacteria; and 61 corresponded to bla(NDM), 39 to bla(KPC,) and 3 to bla(IMP). According to their molecular structure, 64 were metallo-ß-lactamases and 39 were serine-ß-lactamases. Of the total reports, 84 analyzed Pseudomonas aeruginosa: 79 corresponded to bla(IMP), 4 to bla(VIM), and 1 to bla(GES.) Of the total reports, 126 analyzed Acinetobacter baumannii: 55 corresponded to bla(OXA-23), 66 to bla(OXA-24), 3 to bla(NDM,) and 2 to bla(OXA-143). CONCLUSIONS. There is a limited number of publications about carbapenemases among patients in Peru. The genotype reports come primarily from hospitals in the country’s capital. This is the first review that aims to identify the types of carbapenemases reported in enterobacteria, P. aeruginosa, and A. baummani. Organización Panamericana de la Salud 2020-09-23 /pmc/articles/PMC7498286/ /pubmed/32973907 http://dx.doi.org/10.26633/RPSP.2020.61 Text en https://creativecommons.org/licenses/by-nc-nd/3.0/igo/legalcode Este es un artículo de acceso abierto distribuido bajo los términos de la licencia Creative Commons Attribution-NonCommercial-NoDerivs 3.0 IGO, que permite su uso, distribución y reproducción en cualquier medio, siempre que el trabajo original se cite de la manera adecuada. No se permiten modificaciones a los artículos ni su uso comercial. Al reproducir un artículo no debe haber ningún indicio de que la OPS o el artículo avalan a una organización o un producto específico. El uso del logo de la OPS no está permitido. Esta leyenda debe conservarse, junto con la URL original del artículo. |
spellingShingle | Revisión Sistemática Angles-Yanqui, Eddie Huaringa-Marcelo, Jorge Sacsaquispe-Contreras, Rosa Pampa-Espinoza, Luis Panorama de las carbapenemasas en Perú |
title | Panorama de las carbapenemasas en Perú |
title_full | Panorama de las carbapenemasas en Perú |
title_fullStr | Panorama de las carbapenemasas en Perú |
title_full_unstemmed | Panorama de las carbapenemasas en Perú |
title_short | Panorama de las carbapenemasas en Perú |
title_sort | panorama de las carbapenemasas en perú |
topic | Revisión Sistemática |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498286/ https://www.ncbi.nlm.nih.gov/pubmed/32973907 http://dx.doi.org/10.26633/RPSP.2020.61 |
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