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A fully-automated method discovers loss of mouse-lethal and human-monogenic disease genes in 58 mammals
Gene losses provide an insightful route for studying the morphological and physiological adaptations of species, but their discovery is challenging. Existing genome annotation tools focus on annotating intact genes and do not attempt to distinguish nonfunctional genes from genes missing annotation d...
Autores principales: | Turakhia, Yatish, Chen, Heidi I, Marcovitz, Amir, Bejerano, Gill |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498332/ https://www.ncbi.nlm.nih.gov/pubmed/32614390 http://dx.doi.org/10.1093/nar/gkaa550 |
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