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The chromatin-binding protein PHF6 functions as an E3 ubiquitin ligase of H2BK120 via H2BK12Ac recognition for activation of trophectodermal genes

Epigenetic regulation is important for establishing lineage-specific gene expression during early development. Although signaling pathways have been well-studied for regulation of trophectoderm reprogramming, epigenetic regulation of trophectodermal genes with histone modification dynamics have been...

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Detalles Bibliográficos
Autores principales: Oh, Sungryong, Boo, Kyungjin, Kim, Jaebeom, Baek, Seon Ah, Jeon, Yoon, You, Junghyun, Lee, Ho, Choi, Hee-Jung, Park, Daechan, Lee, Ji Min, Baek, Sung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498345/
https://www.ncbi.nlm.nih.gov/pubmed/32735658
http://dx.doi.org/10.1093/nar/gkaa626

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