Thyroid disorders and SARS-CoV-2 infection: From pathophysiological mechanism to patient management

The World Health Organization (WHO) declared the COVID-19 epidemic to be a global pandemic in March 2020. COVID-19 is an infection caused by SARS-CoV-2, a coronavirus that utilizes the angiotensin-2 converting enzyme to penetrate thyroid and pituitary cells, and may result in a “cytokine storm”. Bas...

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Autor principal: Caron, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498405/
https://www.ncbi.nlm.nih.gov/pubmed/32950466
http://dx.doi.org/10.1016/j.ando.2020.09.001
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author Caron, Philippe
author_facet Caron, Philippe
author_sort Caron, Philippe
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description The World Health Organization (WHO) declared the COVID-19 epidemic to be a global pandemic in March 2020. COVID-19 is an infection caused by SARS-CoV-2, a coronavirus that utilizes the angiotensin-2 converting enzyme to penetrate thyroid and pituitary cells, and may result in a “cytokine storm”. Based on the pathophysiological involvement of the pituitary-thyroid axis, the current review discusses the diagnosis of abnormal thyroid function test, and the management of patients presenting with thyrotoxicosis, thyroid-associated orbitopathy and hypothyroidism in the context of SARS-CoV-2 infection.
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spelling pubmed-74984052020-09-18 Thyroid disorders and SARS-CoV-2 infection: From pathophysiological mechanism to patient management Caron, Philippe Ann Endocrinol (Paris) Review The World Health Organization (WHO) declared the COVID-19 epidemic to be a global pandemic in March 2020. COVID-19 is an infection caused by SARS-CoV-2, a coronavirus that utilizes the angiotensin-2 converting enzyme to penetrate thyroid and pituitary cells, and may result in a “cytokine storm”. Based on the pathophysiological involvement of the pituitary-thyroid axis, the current review discusses the diagnosis of abnormal thyroid function test, and the management of patients presenting with thyrotoxicosis, thyroid-associated orbitopathy and hypothyroidism in the context of SARS-CoV-2 infection. Elsevier Masson SAS. 2020-10 2020-09-18 /pmc/articles/PMC7498405/ /pubmed/32950466 http://dx.doi.org/10.1016/j.ando.2020.09.001 Text en © 2020 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Caron, Philippe
Thyroid disorders and SARS-CoV-2 infection: From pathophysiological mechanism to patient management
title Thyroid disorders and SARS-CoV-2 infection: From pathophysiological mechanism to patient management
title_full Thyroid disorders and SARS-CoV-2 infection: From pathophysiological mechanism to patient management
title_fullStr Thyroid disorders and SARS-CoV-2 infection: From pathophysiological mechanism to patient management
title_full_unstemmed Thyroid disorders and SARS-CoV-2 infection: From pathophysiological mechanism to patient management
title_short Thyroid disorders and SARS-CoV-2 infection: From pathophysiological mechanism to patient management
title_sort thyroid disorders and sars-cov-2 infection: from pathophysiological mechanism to patient management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498405/
https://www.ncbi.nlm.nih.gov/pubmed/32950466
http://dx.doi.org/10.1016/j.ando.2020.09.001
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