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The physiological roles of tau and Aβ: implications for Alzheimer’s disease pathology and therapeutics

Tau and amyloid beta (Aβ) are the prime suspects for driving pathology in Alzheimer’s disease (AD) and, as such, have become the focus of therapeutic development. Recent research, however, shows that these proteins have been highly conserved throughout evolution and may have crucial, physiological r...

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Detalles Bibliográficos
Autores principales: Kent, Sarah A., Spires-Jones, Tara L., Durrant, Claire S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498448/
https://www.ncbi.nlm.nih.gov/pubmed/32728795
http://dx.doi.org/10.1007/s00401-020-02196-w