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The physiological roles of tau and Aβ: implications for Alzheimer’s disease pathology and therapeutics
Tau and amyloid beta (Aβ) are the prime suspects for driving pathology in Alzheimer’s disease (AD) and, as such, have become the focus of therapeutic development. Recent research, however, shows that these proteins have been highly conserved throughout evolution and may have crucial, physiological r...
Autores principales: | Kent, Sarah A., Spires-Jones, Tara L., Durrant, Claire S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498448/ https://www.ncbi.nlm.nih.gov/pubmed/32728795 http://dx.doi.org/10.1007/s00401-020-02196-w |
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