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Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health
Green tea is a popularly consumed beverage worldwide and contains polyphenols, whose antioxidant activities could improve sperm parameters and fertility thereof. We investigated the effect of green tea on the male rat reproductive system as well as its safety. Male Wistar rats were administered 2 an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498455/ https://www.ncbi.nlm.nih.gov/pubmed/32943691 http://dx.doi.org/10.1038/s41598-020-72319-6 |
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author | Opuwari, Chinyerum Monsees, Thomas |
author_facet | Opuwari, Chinyerum Monsees, Thomas |
author_sort | Opuwari, Chinyerum |
collection | PubMed |
description | Green tea is a popularly consumed beverage worldwide and contains polyphenols, whose antioxidant activities could improve sperm parameters and fertility thereof. We investigated the effect of green tea on the male rat reproductive system as well as its safety. Male Wistar rats were administered 2 and 5% aqueous extract of green tea for 52 days’ ad libitum, while the control group received tap water. Total polyphenol, flavanol, flavonol and soluble solids significantly increased in a concentration-dependent manner in vitro (P < 0.01). Weights of body, testis, epididymis, prostate gland, seminal vesicles, and liver, serum levels of testosterone, ferric reducing antioxidant power, creatinine, and sperm motility, remained unchanged (P > 0.05). Kidney weight, sperm concentration and vitality, spontaneous acrosome reaction increased (P < 0.05), while alanine transaminase and aspartate transaminase levels decreased (P < 0.05). Catalase, superoxide dismutase, glutathione and lipid peroxidation remained unchanged in the testes, liver and kidney (P > 0.05). Histological sections of testis, epididymis, kidney and liver showed no conspicuous alteration. Diameter and epithelial height of seminiferous tubule decreased, while caudal epididymis epithelial height increased (P < 0.01). Consumption of green tea in the conditions used in the present study seems to be safe and improved sperm parameters. However, subtle structural changes observed in the decreased diameter and epithelial height of the seminiferous tubule and increased acrosome reaction needs further investigation. |
format | Online Article Text |
id | pubmed-7498455 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-74984552020-09-18 Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health Opuwari, Chinyerum Monsees, Thomas Sci Rep Article Green tea is a popularly consumed beverage worldwide and contains polyphenols, whose antioxidant activities could improve sperm parameters and fertility thereof. We investigated the effect of green tea on the male rat reproductive system as well as its safety. Male Wistar rats were administered 2 and 5% aqueous extract of green tea for 52 days’ ad libitum, while the control group received tap water. Total polyphenol, flavanol, flavonol and soluble solids significantly increased in a concentration-dependent manner in vitro (P < 0.01). Weights of body, testis, epididymis, prostate gland, seminal vesicles, and liver, serum levels of testosterone, ferric reducing antioxidant power, creatinine, and sperm motility, remained unchanged (P > 0.05). Kidney weight, sperm concentration and vitality, spontaneous acrosome reaction increased (P < 0.05), while alanine transaminase and aspartate transaminase levels decreased (P < 0.05). Catalase, superoxide dismutase, glutathione and lipid peroxidation remained unchanged in the testes, liver and kidney (P > 0.05). Histological sections of testis, epididymis, kidney and liver showed no conspicuous alteration. Diameter and epithelial height of seminiferous tubule decreased, while caudal epididymis epithelial height increased (P < 0.01). Consumption of green tea in the conditions used in the present study seems to be safe and improved sperm parameters. However, subtle structural changes observed in the decreased diameter and epithelial height of the seminiferous tubule and increased acrosome reaction needs further investigation. Nature Publishing Group UK 2020-09-17 /pmc/articles/PMC7498455/ /pubmed/32943691 http://dx.doi.org/10.1038/s41598-020-72319-6 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Opuwari, Chinyerum Monsees, Thomas Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health |
title | Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health |
title_full | Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health |
title_fullStr | Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health |
title_full_unstemmed | Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health |
title_short | Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health |
title_sort | green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498455/ https://www.ncbi.nlm.nih.gov/pubmed/32943691 http://dx.doi.org/10.1038/s41598-020-72319-6 |
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