HDAC8: A Promising Therapeutic Target for Acute Myeloid Leukemia

Histone deacetylase 8 (HDAC8), a class I HDAC that modifies non-histone proteins such as p53, is highly expressed in different hematological neoplasms including a subtype of acute myeloid leukemia (AML) bearing inversion of chromosome 16 [inv(16)]. To investigate HDAC8 contribution to hematopoietic...

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Detalles Bibliográficos
Autores principales: Spreafico, Marco, Gruszka, Alicja M., Valli, Debora, Mazzola, Mara, Deflorian, Gianluca, Quintè, Arianna, Totaro, Maria Grazia, Battaglia, Cristina, Alcalay, Myriam, Marozzi, Anna, Pistocchi, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498549/
https://www.ncbi.nlm.nih.gov/pubmed/33015043
http://dx.doi.org/10.3389/fcell.2020.00844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498549/
https://www.ncbi.nlm.nih.gov/pubmed/33015043
http://dx.doi.org/10.3389/fcell.2020.00844

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