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DRAM1 plays a tumor suppressor role in NSCLC cells by promoting lysosomal degradation of EGFR

Lung cancer is the leading cause of cancer-associated mortality worldwide. DNA damage-regulated autophagy modulator 1 (DRAM1) plays an important roles in autophagy and tumor progression. However, the mechanisms by which DRAM1 inhibits tumor growth are not fully understood. Here, we report that DRAM1...

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Detalles Bibliográficos
Autores principales:	Geng, Ji, Zhang, Rong, Yuan, Xiao, Xu, Haidong, Zhu, Zhou, Wang, Xinxin, Wang, Yan, Xu, Guoqiang, Guo, Wenjie, Wu, Junchao, Qin, Zheng-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498585/ https://www.ncbi.nlm.nih.gov/pubmed/32943616 http://dx.doi.org/10.1038/s41419-020-02979-9

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