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Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection
Unassisted metastasis through the lymphatic system is a mechanism of dissemination thus far ascribed only to cancer cells. Here, we report that Streptococcus pyogenes also hijack lymphatic vessels to escape a local infection site, transiting through sequential lymph nodes and efferent lymphatic vess...
Autores principales: | Siggins, Matthew K., Lynskey, Nicola N., Lamb, Lucy E., Johnson, Louise A., Huse, Kristin K., Pearson, Max, Banerji, Suneale, Turner, Claire E., Woollard, Kevin, Jackson, David G., Sriskandan, Shiranee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498588/ https://www.ncbi.nlm.nih.gov/pubmed/32943639 http://dx.doi.org/10.1038/s41467-020-18454-0 |
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