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Oxidative stress-mediated mitochondrial dysfunction facilitates mesenchymal stem cell senescence in ankylosing spondylitis
Ankylosing spondylitis (AS) is a chronic inflammatory disease possessing a morbid serum microenvironment with enhanced oxidative stress. Long-term exposure to an oxidative environment usually results in cellular senescence alone with cellular dysfunction. Mesenchymal stem cells (MSCs) are a kind of...
Autores principales: | Ye, Guiwen, Xie, Zhongyu, Zeng, Huiqiong, Wang, Peng, Li, Jinteng, Zheng, Guan, Wang, Shan, Cao, Qian, Li, Ming, Liu, Wenjie, Cen, Shuizhong, Li, Zhaofeng, Wu, Yanfeng, Ye, Zhizhong, Shen, Huiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498590/ https://www.ncbi.nlm.nih.gov/pubmed/32943613 http://dx.doi.org/10.1038/s41419-020-02993-x |
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