Team sport, power, and combat athletes are at high genetic risk for coronavirus disease-2019 severity

• Predictive genetic testing of an asymptomatic person has considerable potential to predict future risk of coronavirus disease-2019 (COVID-19) severity. • Risk alleles for COVID-19 severity due to the pleiotropic effects are associated with performance-related traits. • Team sport, power, and comba...

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Detalles Bibliográficos
Autores principales: Ahmetov, Ildus I., Borisov, Oleg V., Semenova, Ekaterina A., Andryushchenko, Oleg N., Andryushchenko, Liliya B., Generozov, Edward V., Pickering, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shanghai University of Sport 2020
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498656/
https://www.ncbi.nlm.nih.gov/pubmed/32745616
http://dx.doi.org/10.1016/j.jshs.2020.07.010
Descripción
Sumario:• Predictive genetic testing of an asymptomatic person has considerable potential to predict future risk of coronavirus disease-2019 (COVID-19) severity. • Risk alleles for COVID-19 severity due to the pleiotropic effects are associated with performance-related traits. • Team sport, power, and combat athletes possess a higher genetic risk for COVID-19 severity than untrained subjects or endurance athletes. • Polygenic risk scores based on 6 gene polymorphisms show a significant geographical variation, putting some countries at greater risk than others.

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