Team sport, power, and combat athletes are at high genetic risk for coronavirus disease-2019 severity

• Predictive genetic testing of an asymptomatic person has considerable potential to predict future risk of coronavirus disease-2019 (COVID-19) severity. • Risk alleles for COVID-19 severity due to the pleiotropic effects are associated with performance-related traits. • Team sport, power, and comba...

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Autores principales: Ahmetov, Ildus I., Borisov, Oleg V., Semenova, Ekaterina A., Andryushchenko, Oleg N., Andryushchenko, Liliya B., Generozov, Edward V., Pickering, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shanghai University of Sport 2020
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498656/
https://www.ncbi.nlm.nih.gov/pubmed/32745616
http://dx.doi.org/10.1016/j.jshs.2020.07.010
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author Ahmetov, Ildus I.
Borisov, Oleg V.
Semenova, Ekaterina A.
Andryushchenko, Oleg N.
Andryushchenko, Liliya B.
Generozov, Edward V.
Pickering, Craig
author_facet Ahmetov, Ildus I.
Borisov, Oleg V.
Semenova, Ekaterina A.
Andryushchenko, Oleg N.
Andryushchenko, Liliya B.
Generozov, Edward V.
Pickering, Craig
author_sort Ahmetov, Ildus I.
collection PubMed
description • Predictive genetic testing of an asymptomatic person has considerable potential to predict future risk of coronavirus disease-2019 (COVID-19) severity. • Risk alleles for COVID-19 severity due to the pleiotropic effects are associated with performance-related traits. • Team sport, power, and combat athletes possess a higher genetic risk for COVID-19 severity than untrained subjects or endurance athletes. • Polygenic risk scores based on 6 gene polymorphisms show a significant geographical variation, putting some countries at greater risk than others.
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spelling pubmed-74986562020-09-28 Team sport, power, and combat athletes are at high genetic risk for coronavirus disease-2019 severity Ahmetov, Ildus I. Borisov, Oleg V. Semenova, Ekaterina A. Andryushchenko, Oleg N. Andryushchenko, Liliya B. Generozov, Edward V. Pickering, Craig J Sport Health Sci Letter to the Editor • Predictive genetic testing of an asymptomatic person has considerable potential to predict future risk of coronavirus disease-2019 (COVID-19) severity. • Risk alleles for COVID-19 severity due to the pleiotropic effects are associated with performance-related traits. • Team sport, power, and combat athletes possess a higher genetic risk for COVID-19 severity than untrained subjects or endurance athletes. • Polygenic risk scores based on 6 gene polymorphisms show a significant geographical variation, putting some countries at greater risk than others. Shanghai University of Sport 2020-09 2020-07-31 /pmc/articles/PMC7498656/ /pubmed/32745616 http://dx.doi.org/10.1016/j.jshs.2020.07.010 Text en © 2020 Published by Elsevier B.V. on behalf of Shanghai University of Sport. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Letter to the Editor
Ahmetov, Ildus I.
Borisov, Oleg V.
Semenova, Ekaterina A.
Andryushchenko, Oleg N.
Andryushchenko, Liliya B.
Generozov, Edward V.
Pickering, Craig
Team sport, power, and combat athletes are at high genetic risk for coronavirus disease-2019 severity
title Team sport, power, and combat athletes are at high genetic risk for coronavirus disease-2019 severity
title_full Team sport, power, and combat athletes are at high genetic risk for coronavirus disease-2019 severity
title_fullStr Team sport, power, and combat athletes are at high genetic risk for coronavirus disease-2019 severity
title_full_unstemmed Team sport, power, and combat athletes are at high genetic risk for coronavirus disease-2019 severity
title_short Team sport, power, and combat athletes are at high genetic risk for coronavirus disease-2019 severity
title_sort team sport, power, and combat athletes are at high genetic risk for coronavirus disease-2019 severity
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498656/
https://www.ncbi.nlm.nih.gov/pubmed/32745616
http://dx.doi.org/10.1016/j.jshs.2020.07.010
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