Commentary on “The tortuous path of lactate shuttle discovery: From cinders and boards to the lab and ICU”

• Lactate is formed in skeletal muscles during fully oxygenated conditions. • Lactate shuttling between cells (known as the lactate shuttle) provides several important purposes for lactate (i.e., source of energy, gluconeogenic precursor, and signaling molecule). • Importantly, infusion of exogenous...

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Detalles Bibliográficos
Autor principal: Powers, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shanghai University of Sport 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498666/
https://www.ncbi.nlm.nih.gov/pubmed/32928448
http://dx.doi.org/10.1016/j.jshs.2020.02.007
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author Powers, Scott K.
author_facet Powers, Scott K.
author_sort Powers, Scott K.
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description • Lactate is formed in skeletal muscles during fully oxygenated conditions. • Lactate shuttling between cells (known as the lactate shuttle) provides several important purposes for lactate (i.e., source of energy, gluconeogenic precursor, and signaling molecule). • Importantly, infusion of exogenous L-lactate is being evaluated in the treatment of a variety of human illnesses (e.g., heart failure, traumatic brain injury, etc.).
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spelling pubmed-74986662020-09-28 Commentary on “The tortuous path of lactate shuttle discovery: From cinders and boards to the lab and ICU” Powers, Scott K. J Sport Health Sci Commentary • Lactate is formed in skeletal muscles during fully oxygenated conditions. • Lactate shuttling between cells (known as the lactate shuttle) provides several important purposes for lactate (i.e., source of energy, gluconeogenic precursor, and signaling molecule). • Importantly, infusion of exogenous L-lactate is being evaluated in the treatment of a variety of human illnesses (e.g., heart failure, traumatic brain injury, etc.). Shanghai University of Sport 2020-09 2020-02-20 /pmc/articles/PMC7498666/ /pubmed/32928448 http://dx.doi.org/10.1016/j.jshs.2020.02.007 Text en © 2020 Published by Elsevier B.V. on behalf of Shanghai University of Sport. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Commentary
Powers, Scott K.
Commentary on “The tortuous path of lactate shuttle discovery: From cinders and boards to the lab and ICU”
title Commentary on “The tortuous path of lactate shuttle discovery: From cinders and boards to the lab and ICU”
title_full Commentary on “The tortuous path of lactate shuttle discovery: From cinders and boards to the lab and ICU”
title_fullStr Commentary on “The tortuous path of lactate shuttle discovery: From cinders and boards to the lab and ICU”
title_full_unstemmed Commentary on “The tortuous path of lactate shuttle discovery: From cinders and boards to the lab and ICU”
title_short Commentary on “The tortuous path of lactate shuttle discovery: From cinders and boards to the lab and ICU”
title_sort commentary on “the tortuous path of lactate shuttle discovery: from cinders and boards to the lab and icu”
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498666/
https://www.ncbi.nlm.nih.gov/pubmed/32928448
http://dx.doi.org/10.1016/j.jshs.2020.02.007
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