The roles of microRNA in redox metabolism and exercise-mediated adaptation

MicroRNAs (miRs) are small regulatory RNA transcripts capable of post-transcriptional silencing of mRNA messages by entering a cellular bimolecular apparatus called RNA-induced silencing complex. miRs are involved in the regulation of cellular processes producing, eliminating or repairing the damage...

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Autores principales: Torma, Ferenc, Gombos, Zoltan, Jokai, Matyas, Berkes, Istvan, Takeda, Masaki, Mimura, Tatsuya, Radak, Zsolt, Gyori, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shanghai University of Sport 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498669/
https://www.ncbi.nlm.nih.gov/pubmed/32780693
http://dx.doi.org/10.1016/j.jshs.2020.03.004
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author Torma, Ferenc
Gombos, Zoltan
Jokai, Matyas
Berkes, Istvan
Takeda, Masaki
Mimura, Tatsuya
Radak, Zsolt
Gyori, Ferenc
author_facet Torma, Ferenc
Gombos, Zoltan
Jokai, Matyas
Berkes, Istvan
Takeda, Masaki
Mimura, Tatsuya
Radak, Zsolt
Gyori, Ferenc
author_sort Torma, Ferenc
collection PubMed
description MicroRNAs (miRs) are small regulatory RNA transcripts capable of post-transcriptional silencing of mRNA messages by entering a cellular bimolecular apparatus called RNA-induced silencing complex. miRs are involved in the regulation of cellular processes producing, eliminating or repairing the damage caused by reactive oxygen species, and they are active players in redox homeostasis. Increased mitochondrial biogenesis, function and hypertrophy of skeletal muscle are important adaptive responses to regular exercise. In the present review, we highlight some of the redox-sensitive regulatory roles of miRs.
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spelling pubmed-74986692020-09-28 The roles of microRNA in redox metabolism and exercise-mediated adaptation Torma, Ferenc Gombos, Zoltan Jokai, Matyas Berkes, Istvan Takeda, Masaki Mimura, Tatsuya Radak, Zsolt Gyori, Ferenc J Sport Health Sci Review MicroRNAs (miRs) are small regulatory RNA transcripts capable of post-transcriptional silencing of mRNA messages by entering a cellular bimolecular apparatus called RNA-induced silencing complex. miRs are involved in the regulation of cellular processes producing, eliminating or repairing the damage caused by reactive oxygen species, and they are active players in redox homeostasis. Increased mitochondrial biogenesis, function and hypertrophy of skeletal muscle are important adaptive responses to regular exercise. In the present review, we highlight some of the redox-sensitive regulatory roles of miRs. Shanghai University of Sport 2020-09 2020-03-19 /pmc/articles/PMC7498669/ /pubmed/32780693 http://dx.doi.org/10.1016/j.jshs.2020.03.004 Text en © 2020 Published by Elsevier B.V. on behalf of Shanghai University of Sport. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Torma, Ferenc
Gombos, Zoltan
Jokai, Matyas
Berkes, Istvan
Takeda, Masaki
Mimura, Tatsuya
Radak, Zsolt
Gyori, Ferenc
The roles of microRNA in redox metabolism and exercise-mediated adaptation
title The roles of microRNA in redox metabolism and exercise-mediated adaptation
title_full The roles of microRNA in redox metabolism and exercise-mediated adaptation
title_fullStr The roles of microRNA in redox metabolism and exercise-mediated adaptation
title_full_unstemmed The roles of microRNA in redox metabolism and exercise-mediated adaptation
title_short The roles of microRNA in redox metabolism and exercise-mediated adaptation
title_sort roles of microrna in redox metabolism and exercise-mediated adaptation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498669/
https://www.ncbi.nlm.nih.gov/pubmed/32780693
http://dx.doi.org/10.1016/j.jshs.2020.03.004
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