Cargando…
The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective
Over the past decade, the development of high-efficacy disease-modifying therapies (DMTs) has been responsible for more effective management of relapsing-remitting multiple sclerosis (RRMS). However, the gaps in optimal care for this complex disease remain. Alemtuzumab (Lemtrada®) is a highly effica...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498833/ https://www.ncbi.nlm.nih.gov/pubmed/32973927 http://dx.doi.org/10.1177/1756286420954119 |
_version_ | 1783583597690617856 |
---|---|
author | Alroughani, Raed Van Wijmeersch, Bart Al Khaboori, Jabber Alsharoqi, Isa Ahmed Ahmed, Samar F. Hassan, Ali Inshasi, Jihad Krieger, Derk W. Shakra, Mustafa Shatila, Ahmed Osman Szolics, Miklos Khallaf, Mohamed Ezzat, Aly |
author_facet | Alroughani, Raed Van Wijmeersch, Bart Al Khaboori, Jabber Alsharoqi, Isa Ahmed Ahmed, Samar F. Hassan, Ali Inshasi, Jihad Krieger, Derk W. Shakra, Mustafa Shatila, Ahmed Osman Szolics, Miklos Khallaf, Mohamed Ezzat, Aly |
author_sort | Alroughani, Raed |
collection | PubMed |
description | Over the past decade, the development of high-efficacy disease-modifying therapies (DMTs) has been responsible for more effective management of relapsing-remitting multiple sclerosis (RRMS). However, the gaps in optimal care for this complex disease remain. Alemtuzumab (Lemtrada®) is a highly efficacious DMT that shows better patient outcomes and therapeutic benefits, but its use is under-recognized in the Gulf region. Experts in the care of multiple sclerosis shared their opinions based on study data and daily clinical experience in identifying the appropriate patient profile suitable for alemtuzumab’s therapeutic benefits. Age, disease activity and severity, disability status, physician experience, and economic condition are some of the key indicators for alemtuzumab use. |
format | Online Article Text |
id | pubmed-7498833 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-74988332020-09-23 The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective Alroughani, Raed Van Wijmeersch, Bart Al Khaboori, Jabber Alsharoqi, Isa Ahmed Ahmed, Samar F. Hassan, Ali Inshasi, Jihad Krieger, Derk W. Shakra, Mustafa Shatila, Ahmed Osman Szolics, Miklos Khallaf, Mohamed Ezzat, Aly Ther Adv Neurol Disord Review Over the past decade, the development of high-efficacy disease-modifying therapies (DMTs) has been responsible for more effective management of relapsing-remitting multiple sclerosis (RRMS). However, the gaps in optimal care for this complex disease remain. Alemtuzumab (Lemtrada®) is a highly efficacious DMT that shows better patient outcomes and therapeutic benefits, but its use is under-recognized in the Gulf region. Experts in the care of multiple sclerosis shared their opinions based on study data and daily clinical experience in identifying the appropriate patient profile suitable for alemtuzumab’s therapeutic benefits. Age, disease activity and severity, disability status, physician experience, and economic condition are some of the key indicators for alemtuzumab use. SAGE Publications 2020-09-16 /pmc/articles/PMC7498833/ /pubmed/32973927 http://dx.doi.org/10.1177/1756286420954119 Text en © The Author(s), 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review Alroughani, Raed Van Wijmeersch, Bart Al Khaboori, Jabber Alsharoqi, Isa Ahmed Ahmed, Samar F. Hassan, Ali Inshasi, Jihad Krieger, Derk W. Shakra, Mustafa Shatila, Ahmed Osman Szolics, Miklos Khallaf, Mohamed Ezzat, Aly The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective |
title | The use of alemtuzumab in patients with relapsing-remitting multiple
sclerosis: the Gulf perspective |
title_full | The use of alemtuzumab in patients with relapsing-remitting multiple
sclerosis: the Gulf perspective |
title_fullStr | The use of alemtuzumab in patients with relapsing-remitting multiple
sclerosis: the Gulf perspective |
title_full_unstemmed | The use of alemtuzumab in patients with relapsing-remitting multiple
sclerosis: the Gulf perspective |
title_short | The use of alemtuzumab in patients with relapsing-remitting multiple
sclerosis: the Gulf perspective |
title_sort | use of alemtuzumab in patients with relapsing-remitting multiple
sclerosis: the gulf perspective |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498833/ https://www.ncbi.nlm.nih.gov/pubmed/32973927 http://dx.doi.org/10.1177/1756286420954119 |
work_keys_str_mv | AT alroughaniraed theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT vanwijmeerschbart theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT alkhaboorijabber theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT alsharoqiisaahmed theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT ahmedsamarf theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT hassanali theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT inshasijihad theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT kriegerderkw theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT shakramustafa theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT shatilaahmedosman theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT szolicsmiklos theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT khallafmohamed theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT ezzataly theuseofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT alroughaniraed useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT vanwijmeerschbart useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT alkhaboorijabber useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT alsharoqiisaahmed useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT ahmedsamarf useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT hassanali useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT inshasijihad useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT kriegerderkw useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT shakramustafa useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT shatilaahmedosman useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT szolicsmiklos useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT khallafmohamed useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective AT ezzataly useofalemtuzumabinpatientswithrelapsingremittingmultiplesclerosisthegulfperspective |