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The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective

Over the past decade, the development of high-efficacy disease-modifying therapies (DMTs) has been responsible for more effective management of relapsing-remitting multiple sclerosis (RRMS). However, the gaps in optimal care for this complex disease remain. Alemtuzumab (Lemtrada®) is a highly effica...

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Autores principales: Alroughani, Raed, Van Wijmeersch, Bart, Al Khaboori, Jabber, Alsharoqi, Isa Ahmed, Ahmed, Samar F., Hassan, Ali, Inshasi, Jihad, Krieger, Derk W., Shakra, Mustafa, Shatila, Ahmed Osman, Szolics, Miklos, Khallaf, Mohamed, Ezzat, Aly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498833/
https://www.ncbi.nlm.nih.gov/pubmed/32973927
http://dx.doi.org/10.1177/1756286420954119
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author Alroughani, Raed
Van Wijmeersch, Bart
Al Khaboori, Jabber
Alsharoqi, Isa Ahmed
Ahmed, Samar F.
Hassan, Ali
Inshasi, Jihad
Krieger, Derk W.
Shakra, Mustafa
Shatila, Ahmed Osman
Szolics, Miklos
Khallaf, Mohamed
Ezzat, Aly
author_facet Alroughani, Raed
Van Wijmeersch, Bart
Al Khaboori, Jabber
Alsharoqi, Isa Ahmed
Ahmed, Samar F.
Hassan, Ali
Inshasi, Jihad
Krieger, Derk W.
Shakra, Mustafa
Shatila, Ahmed Osman
Szolics, Miklos
Khallaf, Mohamed
Ezzat, Aly
author_sort Alroughani, Raed
collection PubMed
description Over the past decade, the development of high-efficacy disease-modifying therapies (DMTs) has been responsible for more effective management of relapsing-remitting multiple sclerosis (RRMS). However, the gaps in optimal care for this complex disease remain. Alemtuzumab (Lemtrada®) is a highly efficacious DMT that shows better patient outcomes and therapeutic benefits, but its use is under-recognized in the Gulf region. Experts in the care of multiple sclerosis shared their opinions based on study data and daily clinical experience in identifying the appropriate patient profile suitable for alemtuzumab’s therapeutic benefits. Age, disease activity and severity, disability status, physician experience, and economic condition are some of the key indicators for alemtuzumab use.
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spelling pubmed-74988332020-09-23 The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective Alroughani, Raed Van Wijmeersch, Bart Al Khaboori, Jabber Alsharoqi, Isa Ahmed Ahmed, Samar F. Hassan, Ali Inshasi, Jihad Krieger, Derk W. Shakra, Mustafa Shatila, Ahmed Osman Szolics, Miklos Khallaf, Mohamed Ezzat, Aly Ther Adv Neurol Disord Review Over the past decade, the development of high-efficacy disease-modifying therapies (DMTs) has been responsible for more effective management of relapsing-remitting multiple sclerosis (RRMS). However, the gaps in optimal care for this complex disease remain. Alemtuzumab (Lemtrada®) is a highly efficacious DMT that shows better patient outcomes and therapeutic benefits, but its use is under-recognized in the Gulf region. Experts in the care of multiple sclerosis shared their opinions based on study data and daily clinical experience in identifying the appropriate patient profile suitable for alemtuzumab’s therapeutic benefits. Age, disease activity and severity, disability status, physician experience, and economic condition are some of the key indicators for alemtuzumab use. SAGE Publications 2020-09-16 /pmc/articles/PMC7498833/ /pubmed/32973927 http://dx.doi.org/10.1177/1756286420954119 Text en © The Author(s), 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Alroughani, Raed
Van Wijmeersch, Bart
Al Khaboori, Jabber
Alsharoqi, Isa Ahmed
Ahmed, Samar F.
Hassan, Ali
Inshasi, Jihad
Krieger, Derk W.
Shakra, Mustafa
Shatila, Ahmed Osman
Szolics, Miklos
Khallaf, Mohamed
Ezzat, Aly
The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective
title The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective
title_full The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective
title_fullStr The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective
title_full_unstemmed The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective
title_short The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective
title_sort use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the gulf perspective
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498833/
https://www.ncbi.nlm.nih.gov/pubmed/32973927
http://dx.doi.org/10.1177/1756286420954119
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