Neoadjuvant chemotherapy with paclitaxel/carboplatin/bevacizumab in advanced vulvar cancer: Time to rethink standard of care?

Vulvar cancer remains a rare entity and treatment options for advanced disease are limited. This case report highlights the excellent response of two patients with FIGO Stage IV vulvar cancer treated with neoadjuvant paclitaxel/carboplatin/bevacizumab chemotherapy. While definitive conclusions are i...

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Detalles Bibliográficos
Autores principales: Klavans, Madison R., Erickson, Sarah H., Modesitt, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498849/
https://www.ncbi.nlm.nih.gov/pubmed/32984493
http://dx.doi.org/10.1016/j.gore.2020.100631
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author Klavans, Madison R.
Erickson, Sarah H.
Modesitt, Susan C.
author_facet Klavans, Madison R.
Erickson, Sarah H.
Modesitt, Susan C.
author_sort Klavans, Madison R.
collection PubMed
description Vulvar cancer remains a rare entity and treatment options for advanced disease are limited. This case report highlights the excellent response of two patients with FIGO Stage IV vulvar cancer treated with neoadjuvant paclitaxel/carboplatin/bevacizumab chemotherapy. While definitive conclusions are impossible, neoadjuvant chemotherapy may ultimately prove to be a better initial treatment option for locally advanced disease in terms of quality of life and response compared to the traditional chemoradiation regimens.
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spelling pubmed-74988492020-09-25 Neoadjuvant chemotherapy with paclitaxel/carboplatin/bevacizumab in advanced vulvar cancer: Time to rethink standard of care? Klavans, Madison R. Erickson, Sarah H. Modesitt, Susan C. Gynecol Oncol Rep Case Report Vulvar cancer remains a rare entity and treatment options for advanced disease are limited. This case report highlights the excellent response of two patients with FIGO Stage IV vulvar cancer treated with neoadjuvant paclitaxel/carboplatin/bevacizumab chemotherapy. While definitive conclusions are impossible, neoadjuvant chemotherapy may ultimately prove to be a better initial treatment option for locally advanced disease in terms of quality of life and response compared to the traditional chemoradiation regimens. Elsevier 2020-08-25 /pmc/articles/PMC7498849/ /pubmed/32984493 http://dx.doi.org/10.1016/j.gore.2020.100631 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Klavans, Madison R.
Erickson, Sarah H.
Modesitt, Susan C.
Neoadjuvant chemotherapy with paclitaxel/carboplatin/bevacizumab in advanced vulvar cancer: Time to rethink standard of care?
title Neoadjuvant chemotherapy with paclitaxel/carboplatin/bevacizumab in advanced vulvar cancer: Time to rethink standard of care?
title_full Neoadjuvant chemotherapy with paclitaxel/carboplatin/bevacizumab in advanced vulvar cancer: Time to rethink standard of care?
title_fullStr Neoadjuvant chemotherapy with paclitaxel/carboplatin/bevacizumab in advanced vulvar cancer: Time to rethink standard of care?
title_full_unstemmed Neoadjuvant chemotherapy with paclitaxel/carboplatin/bevacizumab in advanced vulvar cancer: Time to rethink standard of care?
title_short Neoadjuvant chemotherapy with paclitaxel/carboplatin/bevacizumab in advanced vulvar cancer: Time to rethink standard of care?
title_sort neoadjuvant chemotherapy with paclitaxel/carboplatin/bevacizumab in advanced vulvar cancer: time to rethink standard of care?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498849/
https://www.ncbi.nlm.nih.gov/pubmed/32984493
http://dx.doi.org/10.1016/j.gore.2020.100631
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AT modesittsusanc neoadjuvantchemotherapywithpaclitaxelcarboplatinbevacizumabinadvancedvulvarcancertimetorethinkstandardofcare

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