Cargando…

Modulating endothelial adhesion and migration impacts stem cell therapies efficacy

BACKGROUND: Limited knowledge of stem cell therapies` mechanisms of action hampers their sustainable implementation into the clinic. Specifically, the interactions of transplanted stem cells with the host vasculature and its implications for their therapeutic efficacy are not elucidated. We tested w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schäfer, Richard, Schwab, Matthias, Siegel, Georg, von Ameln-Mayerhofer, Andreas, Buadze, Marine, Lourhmati, Ali, Wendel, Hans-Peter, Kluba, Torsten, Krueger, Marcel A., Calaminus, Carsten, Scheer, Eva, Dominici, Massimo, Grisendi, Giulia, Doeppner, Thorsten R., Schlechter, Jana, Finzel, Anne Kathrin, Gross, Dominic, Klaffschenkel, Roland, Gehring, Frank K., Spohn, Gabriele, Kretschmer, Anja, Bieback, Karen, Krämer-Albers, Eva-Maria, Barth, Kerstin, Eckert, Anne, Elser, Stefanie, Schmehl, Joerg, Claussen, Claus D., Seifried, Erhard, Hermann, Dirk M., Northoff, Hinnak, Danielyan, Lusine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498853/ https://www.ncbi.nlm.nih.gov/pubmed/32942121 http://dx.doi.org/10.1016/j.ebiom.2020.102987

Ejemplares similares

Cell motility and migration as determinants of stem cell efficacy
por: Danielyan, Lusine, et al.
Publicado: (2020)

Phenotype, donor age and gender affect function of human bone marrow-derived mesenchymal stromal cells
por: Siegel, Georg, et al.
Publicado: (2013)

Age-Dependent Astroglial Vulnerability to Hypoxia and Glutamate: The Role for Erythropoietin
por: Lourhmati, Ali, et al.
Publicado: (2013)

Functional investigations on human mesenchymal stem cells exposed to magnetic fields and labeled with clinically approved iron nanoparticles
por: Schäfer, Richard, et al.
Publicado: (2010)

More Human BM-MSC With Similar Subpopulation Composition and Functional Characteristics Can Be Produced With a GMP-Compatible Fabric Filter System Compared to Density Gradient Technique
por: Spohn, Gabriele, et al.
Publicado: (2021)

Neuroprotective, Neurogenic, and Amyloid Beta Reducing Effect of a Novel Alpha 2-Adrenoblocker, Mesedin, on Astroglia and Neuronal Progenitors upon Hypoxia and Glutamate Exposure
por: Melkonyan, Magda M., et al.
Publicado: (2017)

Change Management
por: von Ameln, Falko, et al.
Publicado: (2023)

Keratinocytes as Depository of Ammonium-Inducible Glutamine Synthetase: Age- and Anatomy-Dependent Distribution in Human and Rat Skin
por: Danielyan, Lusine, et al.
Publicado: (2009)

Correction: Keratinocytes as Depository of Ammonium-Inducible Glutamine Synthetase: Age- and Anatomy-Dependent Distribution in Human and Rat Skin
por: Danielyan, Lusine, et al.
Publicado: (2009)

Losartan Improves Memory, Neurogenesis and Cell Motility in Transgenic Alzheimer’s Mice
por: Drews, Henning Johannes, et al.
Publicado: (2021)

Utilisation of Quartz Crystal Microbalance Sensors with Dissipation (QCM-D) for a Clauss Fibrinogen Assay in Comparison with Common Coagulation Reference Methods
por: Oberfrank, Stephanie, et al.
Publicado: (2016)

Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver
por: Buniatian, Gayane Hrachia, et al.
Publicado: (2020)

Common Neuroprotective Effects of Endothelin Receptor A Blockade and Erythropoietin During Hypoxia-Associated Cell Injury. Perspectives of Combined Treatment
por: Danielyan, Lusine, et al.
Publicado: (2006)

Serum Amyloid Beta42 Is Not Eliminated by the Cirrhotic Liver: A Pilot Study
por: Wiest, Reiner, et al.
Publicado: (2021)

Intranasal Administration of Mesenchymal Stem Cells Ameliorates the Abnormal Dopamine Transmission System and Inflammatory Reaction in the R6/2 Mouse Model of Huntington Disease
por: Yu-Taeger, Libo, et al.
Publicado: (2019)

Pooled human bone marrow-derived mesenchymal stromal cells with defined trophic factors cargo promote dermal wound healing in diabetic rats by improved vascularization and dynamic recruitment of M2-like macrophages
por: Willer, Hélène, et al.
Publicado: (2022)

Hyperforin, an Anti-Inflammatory Constituent from St. John's Wort, Inhibits Microsomal Prostaglandin E(2) Synthase-1 and Suppresses Prostaglandin E(2) Formation in vivo
por: Koeberle, Andreas, et al.
Publicado: (2011)

Characterization of Seeding Conditions for Studies on Differentiation Patterns of Subventricular Zone Derived Neurospheres
por: Sanchez-Mendoza, Eduardo H., et al.
Publicado: (2016)

Harnessing retinal phagocytes to combat pathological neovascularization in ischemic retinopathies?
por: Klotzsche-von Ameln, Anne, et al.
Publicado: (2022)

On the same team: A call for increased medicolegal knowledge exchanges between forensic psychiatry and sports psychiatry
por: Smith, Alexander James, et al.
Publicado: (2022)

Peculiarities of situational and personal anxiety degree in the schoolchildren with ENT chronic diseases
por: Mardiyan, Marine, et al.
Publicado: (2017)

MSH2 and CXCR4 involvement in malignant VIPoma
por: Müller, Sven, et al.
Publicado: (2012)

Real-time measurement of Plasmodium falciparum-infected erythrocyte cytoadhesion with a quartz crystal microbalance
por: Kömpf, Daniela, et al.
Publicado: (2016)

Neural precursor cells in the ischemic brain – integration, cellular crosstalk, and consequences for stroke recovery
por: Hermann, Dirk M., et al.
Publicado: (2014)

Gamasid Ticks as Vectors of Tularemia in the Southeast of Armenia
por: Manucharyan, Arsen, et al.
Publicado: (2023)

Clinically Relevant Interactions with Anti-Infectives on Intensive Care Units—A Multicenter Delphi Study
por: Koeck, Joachim Andreas, et al.
Publicado: (2021)

Cellular prion protein promotes post-ischemic neuronal survival, angioneurogenesis and enhances neural progenitor cell homing via proteasome inhibition
por: Doeppner, T R, et al.
Publicado: (2015)

Variant rs1801157 in the 3’UTR of SDF-1ß Does Not Explain Variability of Healthy-Donor G-CSF Responsiveness
por: Schulz, Miriam, et al.
Publicado: (2015)

Sex-specific variation in signaling pathways and gene expression patterns in human leukocytes in response to endotoxin and exercise
por: Abbasi, Asghar, et al.
Publicado: (2016)

Interplay between Endothelin and Erythropoietin in Astroglia: The Role in Protection against Hypoxia
por: Schäfer, Richard, et al.
Publicado: (2014)

The Novel Alpha-2 Adrenoceptor Inhibitor Beditin Reduces Cytotoxicity and Huntingtin Aggregates in Cell Models of Huntington’s Disease
por: Singer, Elisabeth, et al.
Publicado: (2021)

Combining Intra- and Interindividual Approaches in Epistemic Beliefs Research
por: Rosman, Tom, et al.
Publicado: (2020)

Alpha2-Adrenoblockers Regulate Development of Oxidative Stress and Cognitive Behaviour of Rats under Chronic Acoustic Stress Conditions
por: Melkonyan, Magdalina, et al.
Publicado: (2021)

Intranasal Delivery of Oncolytic Adenovirus XVir-N-31 via Optimized Shuttle Cells Significantly Extends Survival of Glioblastoma-Bearing Mice
por: El-Ayoubi, Ali, et al.
Publicado: (2023)

Intravascular Application of Labelled Cell Spheroids: An Approach for Ischemic Peripheral Artery Disease
por: Schmehl, Jörg, et al.
Publicado: (2021)

NCO-sP(EO-stat-PO) Coatings on Gold Sensors—a QCM Study of Hemocompatibility
por: Sinn, Stefan, et al.
Publicado: (2011)

Führen und Entscheiden unter Unsicherheit
por: von Ameln, Falko
Publicado: (2021)

Intranasal Treatment of Central Nervous System Dysfunction in Humans
por: Chapman, Colin D., et al.
Publicado: (2012)

Quantitation of progenitor cell populations and growth factors after bone marrow aspirate concentration
por: Schäfer, Richard, et al.
Publicado: (2019)

Role of mesenchymal stem cells in osteosarcoma and metabolic reprogramming of tumor cells
por: Bonuccelli, Gloria, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7ket3m88mlgofs4qb36lg5eq2r