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Multicenter experience with photoselective vaporization of the prostate on men taking novel oral anticoagulants
OBJECTIVE: Photoselective vaporization of the prostate (PVP) is a widely performed surgical procedure for benign prostatic obstruction. This approach has become particular favoured for men on anti-platelet and anticoagulation agents such as clopidogrel and warfarin but there is minimal published exp...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Second Military Medical University
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498936/ https://www.ncbi.nlm.nih.gov/pubmed/32995278 http://dx.doi.org/10.1016/j.ajur.2019.07.005 |
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author | Sachs, Brooke Misrai, Vincent Tabatabaei, Shahin Woo, Henry H. |
author_facet | Sachs, Brooke Misrai, Vincent Tabatabaei, Shahin Woo, Henry H. |
author_sort | Sachs, Brooke |
collection | PubMed |
description | OBJECTIVE: Photoselective vaporization of the prostate (PVP) is a widely performed surgical procedure for benign prostatic obstruction. This approach has become particular favoured for men on anti-platelet and anticoagulation agents such as clopidogrel and warfarin but there is minimal published experience in the setting of novel oral anticoagulants (NOACs). This study was to examine the perioperative outcomes in men on NOACs undergoing PVP, with particular reference to perioperative morbidity. METHODS: A retrospective analysis of PVP datasets was undertaken from three centres in Sydney (Australia), Toulouse (France) and Boston (USA). Subjects who had been treated whilst on NOACs without discontinuation or bridging were identified. Perioperative outcomes and treatment parameters were examined and morbidity recorded according to Clavien-Dindo (CD) classification. RESULTS: There were a total of 20 subjects who had undergone PVP whilst NOACs had been continued during the perioperative period. The mean age was 77±6.5 years. The mean prostate volume, energy utilization and vaporisation time was 94±56 mL, 301±211 kJ, and 35±21 min respectively. The mean postoperative duration of catheterization and duration of hospitalization was 2.2±2.4 days and 2.4±2.4 days respectively. There was a single episode of urinary tract infection and four subjects required re-catheterisation for non-hematuric retentions. CONCLUSIONS: This study supports the safety of men on NOACs undergoing PVP. Whilst this study represents the largest experience of PVP in these men, larger studies are necessary to confirm the safety of PVP in this group of men undergoing BPH-related surgery. |
format | Online Article Text |
id | pubmed-7498936 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Second Military Medical University |
record_format | MEDLINE/PubMed |
spelling | pubmed-74989362020-09-28 Multicenter experience with photoselective vaporization of the prostate on men taking novel oral anticoagulants Sachs, Brooke Misrai, Vincent Tabatabaei, Shahin Woo, Henry H. Asian J Urol Original Article OBJECTIVE: Photoselective vaporization of the prostate (PVP) is a widely performed surgical procedure for benign prostatic obstruction. This approach has become particular favoured for men on anti-platelet and anticoagulation agents such as clopidogrel and warfarin but there is minimal published experience in the setting of novel oral anticoagulants (NOACs). This study was to examine the perioperative outcomes in men on NOACs undergoing PVP, with particular reference to perioperative morbidity. METHODS: A retrospective analysis of PVP datasets was undertaken from three centres in Sydney (Australia), Toulouse (France) and Boston (USA). Subjects who had been treated whilst on NOACs without discontinuation or bridging were identified. Perioperative outcomes and treatment parameters were examined and morbidity recorded according to Clavien-Dindo (CD) classification. RESULTS: There were a total of 20 subjects who had undergone PVP whilst NOACs had been continued during the perioperative period. The mean age was 77±6.5 years. The mean prostate volume, energy utilization and vaporisation time was 94±56 mL, 301±211 kJ, and 35±21 min respectively. The mean postoperative duration of catheterization and duration of hospitalization was 2.2±2.4 days and 2.4±2.4 days respectively. There was a single episode of urinary tract infection and four subjects required re-catheterisation for non-hematuric retentions. CONCLUSIONS: This study supports the safety of men on NOACs undergoing PVP. Whilst this study represents the largest experience of PVP in these men, larger studies are necessary to confirm the safety of PVP in this group of men undergoing BPH-related surgery. Second Military Medical University 2020-10 2019-07-30 /pmc/articles/PMC7498936/ /pubmed/32995278 http://dx.doi.org/10.1016/j.ajur.2019.07.005 Text en © 2020 Editorial Office of Asian Journal of Urology. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Sachs, Brooke Misrai, Vincent Tabatabaei, Shahin Woo, Henry H. Multicenter experience with photoselective vaporization of the prostate on men taking novel oral anticoagulants |
title | Multicenter experience with photoselective vaporization of the prostate on men taking novel oral anticoagulants |
title_full | Multicenter experience with photoselective vaporization of the prostate on men taking novel oral anticoagulants |
title_fullStr | Multicenter experience with photoselective vaporization of the prostate on men taking novel oral anticoagulants |
title_full_unstemmed | Multicenter experience with photoselective vaporization of the prostate on men taking novel oral anticoagulants |
title_short | Multicenter experience with photoselective vaporization of the prostate on men taking novel oral anticoagulants |
title_sort | multicenter experience with photoselective vaporization of the prostate on men taking novel oral anticoagulants |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498936/ https://www.ncbi.nlm.nih.gov/pubmed/32995278 http://dx.doi.org/10.1016/j.ajur.2019.07.005 |
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