Vitamin D Receptor Protects Against Dysbiosis and Tumorigenesis via the JAK/STAT Pathway in Intestine

BACKGROUND & AIMS: Vitamin D exerts regulatory roles via vitamin D receptor (VDR) in mucosal immunity, host defense, and inflammation involving host factors and microbiome. Human Vdr gene variation shapes the microbiome and VDR deletion leads to dysbiosis. Low VDR expression and diminished vitam...

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Detalles Bibliográficos
Autores principales: Zhang, Yong-Guo, Lu, Rong, Wu, Shaoping, Chatterjee, Ishita, Zhou, David, Xia, Yinglin, Sun, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498955/
https://www.ncbi.nlm.nih.gov/pubmed/32497792
http://dx.doi.org/10.1016/j.jcmgh.2020.05.010

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