N-Acetylcysteine Reverses Antiretroviral-Mediated Microglial Activation by Attenuating Autophagy-Lysosomal Dysfunction

Successful suppression of viral replication by combined antiretroviral therapy (cART) in HIV-1 infected individuals is paradoxically also accompanied by an increased prevalence of HIV-associated neurocognitive disorders (HAND) in these individuals. HAND is characterized by a state of chronic oxidati...

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Detalles Bibliográficos
Autores principales: Tripathi, Ashutosh, Thangaraj, Annadurai, Chivero, Ernest T., Periyasamy, Palsamy, Burkovetskaya, Maria E., Niu, Fang, Guo, Ming-Lei, Buch, Shilpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498983/
https://www.ncbi.nlm.nih.gov/pubmed/33013619
http://dx.doi.org/10.3389/fneur.2020.00840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498983/
https://www.ncbi.nlm.nih.gov/pubmed/33013619
http://dx.doi.org/10.3389/fneur.2020.00840

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