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N-Acetylcysteine Reverses Antiretroviral-Mediated Microglial Activation by Attenuating Autophagy-Lysosomal Dysfunction
Successful suppression of viral replication by combined antiretroviral therapy (cART) in HIV-1 infected individuals is paradoxically also accompanied by an increased prevalence of HIV-associated neurocognitive disorders (HAND) in these individuals. HAND is characterized by a state of chronic oxidati...
Autores principales: | Tripathi, Ashutosh, Thangaraj, Annadurai, Chivero, Ernest T., Periyasamy, Palsamy, Burkovetskaya, Maria E., Niu, Fang, Guo, Ming-Lei, Buch, Shilpa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498983/ https://www.ncbi.nlm.nih.gov/pubmed/33013619 http://dx.doi.org/10.3389/fneur.2020.00840 |
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