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Synthesis, characterization and computational study on potential inhibitory action of novel azo imidazole derivatives against COVID-19 main protease (M(pro): 6LU7)

A series of six novel imidazole anchored azo-imidazole derivatives (L1-L6) have been prepared by the simple condensation reaction of azo-coupled ortho-vaniline precursor with amino functionalised imidazole derivative and the synthesized derivatives (L1-L6) have been characterized by different analyt...

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Detalles Bibliográficos
Autores principales: Chhetri, Abhijit, Chettri, Sailesh, Rai, Pranesh, Mishra, Dipu Kumar, Sinha, Biswajit, Brahman, Dhiraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499073/
https://www.ncbi.nlm.nih.gov/pubmed/32963413
http://dx.doi.org/10.1016/j.molstruc.2020.129230