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The Results of 16 Years of Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey

OBJECTIVE: Iodine deficiency (ID) continues to be a problem around the world. This study investigated the prevalence of ID and goiter among school-age children in the city center of Antalya, Turkey. The aim was to investigate the effect of an iodization program, which had been running for sixteen ye...

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Autores principales: Çelmeli, Gamze, Çürek, Yusuf, Özen Kücükçetin, İkbal, Arslan Gülten, Zümrüt, Özdem, Sebahat, Akçurin, Sema, Bircan, İffet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499140/
https://www.ncbi.nlm.nih.gov/pubmed/31948188
http://dx.doi.org/10.4274/jcrpe.galenos.2020.2019.0168
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author Çelmeli, Gamze
Çürek, Yusuf
Özen Kücükçetin, İkbal
Arslan Gülten, Zümrüt
Özdem, Sebahat
Akçurin, Sema
Bircan, İffet
author_facet Çelmeli, Gamze
Çürek, Yusuf
Özen Kücükçetin, İkbal
Arslan Gülten, Zümrüt
Özdem, Sebahat
Akçurin, Sema
Bircan, İffet
author_sort Çelmeli, Gamze
collection PubMed
description OBJECTIVE: Iodine deficiency (ID) continues to be a problem around the world. This study investigated the prevalence of ID and goiter among school-age children in the city center of Antalya, Turkey. The aim was to investigate the effect of an iodization program, which had been running for sixteen years, on nutritional iodine status in this population. METHODS: A total of 1,594 school children, aged 6-14 years, were included in this cross-sectional study. ID was evaluated based on median [interquartile range (IQR)] urine iodine/creatine (UI/Cr) (μg/g) ratio and median (IQR) UI concentrations (UIC) (μg/L). UICs were measured using the Sandell-Kolthoff method. Goiter was determined by palpation and staged according to World Health Organization classification. RESULTS: Median (IQR) UIC was found to be 174.69 (119.17-242.83) μg/L, and UIC was found to be lower than 50 μg/L in 6.5% of the population. The median UI/Cr ratio increased from 62.3 to 163.3 μg/g and goiter rates had decreased from 34% to 0.3% over the 16 years of the program. However, 19% were still classified as ID (mild, moderate or severe) and, furthermore, 11.5% were classified as excessive iodine intake. CONCLUSION: Comparison of two cross-sectional studies, carried out 16-years apart, showed that Antalya is no longer an ID region. However, surveillance should be continued and the percentage of ID and iodine excess individuals in the population should be monitored to avoid emerging problems.
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spelling pubmed-74991402020-09-23 The Results of 16 Years of Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey Çelmeli, Gamze Çürek, Yusuf Özen Kücükçetin, İkbal Arslan Gülten, Zümrüt Özdem, Sebahat Akçurin, Sema Bircan, İffet J Clin Res Pediatr Endocrinol Original Article OBJECTIVE: Iodine deficiency (ID) continues to be a problem around the world. This study investigated the prevalence of ID and goiter among school-age children in the city center of Antalya, Turkey. The aim was to investigate the effect of an iodization program, which had been running for sixteen years, on nutritional iodine status in this population. METHODS: A total of 1,594 school children, aged 6-14 years, were included in this cross-sectional study. ID was evaluated based on median [interquartile range (IQR)] urine iodine/creatine (UI/Cr) (μg/g) ratio and median (IQR) UI concentrations (UIC) (μg/L). UICs were measured using the Sandell-Kolthoff method. Goiter was determined by palpation and staged according to World Health Organization classification. RESULTS: Median (IQR) UIC was found to be 174.69 (119.17-242.83) μg/L, and UIC was found to be lower than 50 μg/L in 6.5% of the population. The median UI/Cr ratio increased from 62.3 to 163.3 μg/g and goiter rates had decreased from 34% to 0.3% over the 16 years of the program. However, 19% were still classified as ID (mild, moderate or severe) and, furthermore, 11.5% were classified as excessive iodine intake. CONCLUSION: Comparison of two cross-sectional studies, carried out 16-years apart, showed that Antalya is no longer an ID region. However, surveillance should be continued and the percentage of ID and iodine excess individuals in the population should be monitored to avoid emerging problems. Galenos Publishing 2020-09 2020-09-02 /pmc/articles/PMC7499140/ /pubmed/31948188 http://dx.doi.org/10.4274/jcrpe.galenos.2020.2019.0168 Text en ©Copyright 2020 by Turkish Pediatric Endocrinology and Diabetes Society | The Journal of Clinical Research in Pediatric Endocrinology published by Galenos Publishing House. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Çelmeli, Gamze
Çürek, Yusuf
Özen Kücükçetin, İkbal
Arslan Gülten, Zümrüt
Özdem, Sebahat
Akçurin, Sema
Bircan, İffet
The Results of 16 Years of Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey
title The Results of 16 Years of Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey
title_full The Results of 16 Years of Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey
title_fullStr The Results of 16 Years of Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey
title_full_unstemmed The Results of 16 Years of Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey
title_short The Results of 16 Years of Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey
title_sort results of 16 years of iodization: assessment of iodine deficiency among school-age children in antalya, turkey
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499140/
https://www.ncbi.nlm.nih.gov/pubmed/31948188
http://dx.doi.org/10.4274/jcrpe.galenos.2020.2019.0168
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