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Importance of Stability Analysis When Using Nonlinear Semimechanistic Models to Describe Drug‐Induced Hematotoxicity
Stability analysis, often overlooked in pharmacometrics, is essential to explore dynamical systems. The model developed by Friberg et al.(1) to describe drug‐induced hematotoxicity is widely used to support decisions across drug development, and parameter values are often identified from observed bl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499189/ https://www.ncbi.nlm.nih.gov/pubmed/32453487 http://dx.doi.org/10.1002/psp4.12514 |