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APOE2 promotes the development and progression of subretinal neovascularization in age-related macular degeneration via MAPKs signaling pathway
BACKGROUND: Neovascular age-related macular degeneration (nvAMD) is one of the main pathological features of wet AMD. Apolipoprotein E2 is involved in the formation of nvAMD but the molecular mechanism has not been reported. METHODS: The APOE alleles in AMD patients were detected by genotyping. Mous...
Autores principales: | Sun, Yiwen, Song, Ruixia, Ai, Yanliang, Zhu, Jianjun, He, Jun, Dang, Minyan, Li, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499293/ https://www.ncbi.nlm.nih.gov/pubmed/32994736 http://dx.doi.org/10.1016/j.sjbs.2020.06.037 |
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