The triterpenoid sapogenin (2α-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling

Gypenosides, extracts of Gynostemma yixingense, have been traditionally prescribed to improve metabolic syndrome in Asian folk and local traditional medicine hospitals. However, the mechanism of its action remains unclarified. In this work, our results indicated that chronic administration of 2α-OH-...

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Detalles Bibliográficos
Autores principales: Xie, Zhifu, Jiang, Haowen, Liu, Wei, Zhang, Xinwen, Chen, Dakai, Sun, Shuimei, Zhou, Chendong, Liu, Jia, Bao, Sheng, Wang, Xiachang, Zhang, Yinan, Li, Jia, Hu, Lihong, Li, Jingya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499306/
https://www.ncbi.nlm.nih.gov/pubmed/32943612
http://dx.doi.org/10.1038/s41419-020-02974-0

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