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Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules

Trichoepitheliomas (TE) are benign skin tumours of the pilosebaceous apocrine unit with follicular differentiation. Multiple familial trichoepithelioma (MFT) is a considerably rare condition inherited in an autosomal dominant pattern. We present a case of a 15-year-old male who presented with multip...

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Autores principales: Dissanayaka, D. W. V. N., Dassanayaka, D. K. B., Jayasooriya, P. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499335/
https://www.ncbi.nlm.nih.gov/pubmed/32963838
http://dx.doi.org/10.1155/2020/5648647
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author Dissanayaka, D. W. V. N.
Dassanayaka, D. K. B.
Jayasooriya, P. R.
author_facet Dissanayaka, D. W. V. N.
Dassanayaka, D. K. B.
Jayasooriya, P. R.
author_sort Dissanayaka, D. W. V. N.
collection PubMed
description Trichoepitheliomas (TE) are benign skin tumours of the pilosebaceous apocrine unit with follicular differentiation. Multiple familial trichoepithelioma (MFT) is a considerably rare condition inherited in an autosomal dominant pattern. We present a case of a 15-year-old male who presented with multiple papulo-nodular lesions in the central face and a family history of a similar type of lesions from his mother. Significance of consideration of various clinical differential diagnoses with serious pathological outcomes, strategies followed in the diagnosis including histopathological evaluation aided by immunohistochemical investigations, and subsequent challenges that may be faced in the management of MFT in light of the presentation with multiple facial papules are documented in this case report.
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spelling pubmed-74993352020-09-21 Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules Dissanayaka, D. W. V. N. Dassanayaka, D. K. B. Jayasooriya, P. R. Case Rep Dent Case Report Trichoepitheliomas (TE) are benign skin tumours of the pilosebaceous apocrine unit with follicular differentiation. Multiple familial trichoepithelioma (MFT) is a considerably rare condition inherited in an autosomal dominant pattern. We present a case of a 15-year-old male who presented with multiple papulo-nodular lesions in the central face and a family history of a similar type of lesions from his mother. Significance of consideration of various clinical differential diagnoses with serious pathological outcomes, strategies followed in the diagnosis including histopathological evaluation aided by immunohistochemical investigations, and subsequent challenges that may be faced in the management of MFT in light of the presentation with multiple facial papules are documented in this case report. Hindawi 2020-09-07 /pmc/articles/PMC7499335/ /pubmed/32963838 http://dx.doi.org/10.1155/2020/5648647 Text en Copyright © 2020 D. W. V. N. Dissanayaka et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dissanayaka, D. W. V. N.
Dassanayaka, D. K. B.
Jayasooriya, P. R.
Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules
title Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules
title_full Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules
title_fullStr Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules
title_full_unstemmed Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules
title_short Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules
title_sort clinical, histopathological, and management challenges of multiple familial trichoepithelioma: a case report of a patient presenting with multiple facial papules
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499335/
https://www.ncbi.nlm.nih.gov/pubmed/32963838
http://dx.doi.org/10.1155/2020/5648647
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