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Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules
Trichoepitheliomas (TE) are benign skin tumours of the pilosebaceous apocrine unit with follicular differentiation. Multiple familial trichoepithelioma (MFT) is a considerably rare condition inherited in an autosomal dominant pattern. We present a case of a 15-year-old male who presented with multip...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499335/ https://www.ncbi.nlm.nih.gov/pubmed/32963838 http://dx.doi.org/10.1155/2020/5648647 |
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author | Dissanayaka, D. W. V. N. Dassanayaka, D. K. B. Jayasooriya, P. R. |
author_facet | Dissanayaka, D. W. V. N. Dassanayaka, D. K. B. Jayasooriya, P. R. |
author_sort | Dissanayaka, D. W. V. N. |
collection | PubMed |
description | Trichoepitheliomas (TE) are benign skin tumours of the pilosebaceous apocrine unit with follicular differentiation. Multiple familial trichoepithelioma (MFT) is a considerably rare condition inherited in an autosomal dominant pattern. We present a case of a 15-year-old male who presented with multiple papulo-nodular lesions in the central face and a family history of a similar type of lesions from his mother. Significance of consideration of various clinical differential diagnoses with serious pathological outcomes, strategies followed in the diagnosis including histopathological evaluation aided by immunohistochemical investigations, and subsequent challenges that may be faced in the management of MFT in light of the presentation with multiple facial papules are documented in this case report. |
format | Online Article Text |
id | pubmed-7499335 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-74993352020-09-21 Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules Dissanayaka, D. W. V. N. Dassanayaka, D. K. B. Jayasooriya, P. R. Case Rep Dent Case Report Trichoepitheliomas (TE) are benign skin tumours of the pilosebaceous apocrine unit with follicular differentiation. Multiple familial trichoepithelioma (MFT) is a considerably rare condition inherited in an autosomal dominant pattern. We present a case of a 15-year-old male who presented with multiple papulo-nodular lesions in the central face and a family history of a similar type of lesions from his mother. Significance of consideration of various clinical differential diagnoses with serious pathological outcomes, strategies followed in the diagnosis including histopathological evaluation aided by immunohistochemical investigations, and subsequent challenges that may be faced in the management of MFT in light of the presentation with multiple facial papules are documented in this case report. Hindawi 2020-09-07 /pmc/articles/PMC7499335/ /pubmed/32963838 http://dx.doi.org/10.1155/2020/5648647 Text en Copyright © 2020 D. W. V. N. Dissanayaka et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Dissanayaka, D. W. V. N. Dassanayaka, D. K. B. Jayasooriya, P. R. Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules |
title | Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules |
title_full | Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules |
title_fullStr | Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules |
title_full_unstemmed | Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules |
title_short | Clinical, Histopathological, and Management Challenges of Multiple Familial Trichoepithelioma: A Case Report of a Patient Presenting with Multiple Facial Papules |
title_sort | clinical, histopathological, and management challenges of multiple familial trichoepithelioma: a case report of a patient presenting with multiple facial papules |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499335/ https://www.ncbi.nlm.nih.gov/pubmed/32963838 http://dx.doi.org/10.1155/2020/5648647 |
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