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Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective

The structure of the eye is very complex in nature which makes it a challenging task for pharmaceutical researchers to deliver the drug at the desired sites via different routes of administration. The development of the nano-based system helped in delivering the drug in the desired concentration. Im...

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Autores principales: Qamar, Zufika, Qizilbash, Farheen Fatima, Iqubal, Mohammad Kashif, Ali, Asgar, Narang, Jasjeet Kaur, Ali, Javed, Baboota, Sanjula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499345/
https://www.ncbi.nlm.nih.gov/pubmed/31884933
http://dx.doi.org/10.2174/1872211314666191224115211
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author Qamar, Zufika
Qizilbash, Farheen Fatima
Iqubal, Mohammad Kashif
Ali, Asgar
Narang, Jasjeet Kaur
Ali, Javed
Baboota, Sanjula
author_facet Qamar, Zufika
Qizilbash, Farheen Fatima
Iqubal, Mohammad Kashif
Ali, Asgar
Narang, Jasjeet Kaur
Ali, Javed
Baboota, Sanjula
author_sort Qamar, Zufika
collection PubMed
description The structure of the eye is very complex in nature which makes it a challenging task for pharmaceutical researchers to deliver the drug at the desired sites via different routes of administration. The development of the nano-based system helped in delivering the drug in the desired concentration. Improvement in penetration property, bioavailability, and residence time has all been achieved by encapsulating drugs into liposomes, dendrimers, solid lipid nanoparticle, nanostructured lipid carrier, nanoemulsion, and nanosuspension. This review puts emphasis on the need for nanomedicine for ocular drug delivery and recent developments in the field of nanomedicine along with recent patents published in the past few years.
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spelling pubmed-74993452020-10-09 Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective Qamar, Zufika Qizilbash, Farheen Fatima Iqubal, Mohammad Kashif Ali, Asgar Narang, Jasjeet Kaur Ali, Javed Baboota, Sanjula Recent Pat Drug Deliv Formul Article The structure of the eye is very complex in nature which makes it a challenging task for pharmaceutical researchers to deliver the drug at the desired sites via different routes of administration. The development of the nano-based system helped in delivering the drug in the desired concentration. Improvement in penetration property, bioavailability, and residence time has all been achieved by encapsulating drugs into liposomes, dendrimers, solid lipid nanoparticle, nanostructured lipid carrier, nanoemulsion, and nanosuspension. This review puts emphasis on the need for nanomedicine for ocular drug delivery and recent developments in the field of nanomedicine along with recent patents published in the past few years. Bentham Science Publishers 2019-12 2019-12 /pmc/articles/PMC7499345/ /pubmed/31884933 http://dx.doi.org/10.2174/1872211314666191224115211 Text en © 2019 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Qamar, Zufika
Qizilbash, Farheen Fatima
Iqubal, Mohammad Kashif
Ali, Asgar
Narang, Jasjeet Kaur
Ali, Javed
Baboota, Sanjula
Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective
title Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective
title_full Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective
title_fullStr Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective
title_full_unstemmed Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective
title_short Nano-Based Drug Delivery System: Recent Strategies for the Treatment of Ocular Disease and Future Perspective
title_sort nano-based drug delivery system: recent strategies for the treatment of ocular disease and future perspective
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499345/
https://www.ncbi.nlm.nih.gov/pubmed/31884933
http://dx.doi.org/10.2174/1872211314666191224115211
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