Physicochemical Considerations of Tumor Selective Drug Delivery and 
Activity Confinement with Particular Reference to 1,2-Bis(Sulfonyl)-1-Alkylhydrazines Delivery

Hypoxic tumor cell sub-populations are highly resistant to radiotherapy and their presence frequently causes disease recurrence and death. Here, we described the physicochemical properties required to develop superior tumor-targeted hypoxia-activated modular prodrugs that liberate extremely short-li...

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Detalles Bibliográficos
Autores principales: Penketh, Philip, Williamson, Hugh, Shyam, Krishnamurthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499353/
https://www.ncbi.nlm.nih.gov/pubmed/32342817
http://dx.doi.org/10.2174/1567201817666200427215044

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