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Role of HVR1 sequence similarity in the cross-genotypic neutralization of HCV

Despite available treatments, a prophylactic HCV vaccine is needed to achieve elimination targets. HCV vaccine development has faltered largely because the extreme diversity of the virus limits the protective breadth of vaccine elicited antibodies. It is believed that the principle neutralizing epit...

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Detalles Bibliográficos
Autores principales: Mosa, Alexander I., AbouHaidar, Mounir G., Urbanowicz, Richard A., Tavis, John E., Ball, Jonathan K., Feld, Jordan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499410/
https://www.ncbi.nlm.nih.gov/pubmed/32948191
http://dx.doi.org/10.1186/s12985-020-01408-9