Cargando…

Role of HVR1 sequence similarity in the cross-genotypic neutralization of HCV

Despite available treatments, a prophylactic HCV vaccine is needed to achieve elimination targets. HCV vaccine development has faltered largely because the extreme diversity of the virus limits the protective breadth of vaccine elicited antibodies. It is believed that the principle neutralizing epit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mosa, Alexander I., AbouHaidar, Mounir G., Urbanowicz, Richard A., Tavis, John E., Ball, Jonathan K., Feld, Jordan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499410/ https://www.ncbi.nlm.nih.gov/pubmed/32948191 http://dx.doi.org/10.1186/s12985-020-01408-9

Ejemplares similares

Polyvalent immunization elicits a synergistic broadly neutralizing immune response to hypervariable region 1 variants of hepatitis C virus
por: Mosa, Alexander I., et al.
Publicado: (2023)

Evaluation of the immunogenicity of liposome encapsulated HVR1 and NS3 regions of genotype 3 HCV, either singly or in combination
por: Gupte, Gouri M, et al.
Publicado: (2012)

HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice
por: Prentoe, Jannick, et al.
Publicado: (2016)

Hepatitis C virus (HCV) genotype 1b displays higher genetic variability of hypervariable region 1 (HVR1) than genotype 3
por: Janiak, Maciej, et al.
Publicado: (2019)

HvrBase++: a phylogenetic database for primate species
por: Kohl, Jochen, et al.
Publicado: (2006)

Identification of mutations in the HVR1 and PKR-BD regions in HCV-infected patients resistant to PEG-IFNα/RBV therapy
por: Holysz, M., et al.
Publicado: (2015)

Connexin43 as a Tumor Suppressor: Proposed Connexin43 mRNA-circularRNAs-microRNAs Axis Towards Prevention and Early Detection in Breast Cancer
por: Naser Al Deen, Nataly, et al.
Publicado: (2019)

First-in-human phase 1 trial of the safety and immunogenicity of a recombinant adenovirus serotype 5 HVR48 (rAd5HVR48) HIV-1 vaccine
por: Walsh, SR, et al.
Publicado: (2012)

Prevalence of HCV genotypes in district Mardan
por: Afridi, Suliman Qadir, et al.
Publicado: (2013)

A general method for nested RT-PCR amplification and sequencing the complete HCV genotype 1 open reading frame
por: Yao, Ermei, et al.
Publicado: (2005)

How Computational Epitope Mapping Identifies the Interactions between Nanoparticles Derived from Papaya Mosaic Virus Capsid Proteins and Immune System
por: Zamani-Babgohari, Mahbobeh, et al.
Publicado: (2019)

Monoclonal Antibodies Directed toward the Hepatitis C Virus Glycoprotein E2 Detect Antigenic Differences Modulated by the N-Terminal Hypervariable Region 1 (HVR1), HVR2, and Intergenotypic Variable Region
por: Alhammad, Yousef, et al.
Publicado: (2015)

An Inside Look into Biological Miniatures: Molecular Mechanisms of Viroids
por: Venkataraman, Srividhya, et al.
Publicado: (2021)

Development of vaccine for "hepatitis C" (Papaya mosaic virus as an expression vector for foreign epitopes)
por: Raja, Varsha, et al.
Publicado: (2006)

Determinants of influenza and COVID-19 vaccine intent or uptake in Lebanon: a scoping review of the literature
por: Salam, Mahmoud, et al.
Publicado: (2023)

Assessment of inducible clindamycin resistance and Hyper Variable Region (HVR) of mecA gene in clinical staphylococci
por: Khan, Amir Afzal, et al.
Publicado: (2020)

Some maternal lineages of domestic horses may have origins in East Asia revealed with further evidence of mitochondrial genomes and HVR-1 sequences
por: Ma, Hongying, et al.
Publicado: (2018)

Role of the E2 Hypervariable Region (HVR1) in the Immunogenicity of a Recombinant Hepatitis C Virus Vaccine
por: Law, John L. M., et al.
Publicado: (2018)

Hepatitis C Virus (HCV) Infection May Elicit Neutralizing Antibodies Targeting Epitopes Conserved in All Viral Genotypes
por: Mancini, Nicasio, et al.
Publicado: (2009)

Perceived impact of community kitchens on the food security of Syrian refugees and kitchen workers in Lebanon: Qualitative evidence in a displacement context
por: Ibrahim, Nadiya, et al.
Publicado: (2019)

Remaining challenges in HCV elimination
por: Capraru, Camelia, et al.
Publicado: (2021)

Anaphylaxis management: a survey of school and day care nurses in Lebanon
por: Avedissian, Tamar, et al.
Publicado: (2018)

Cash Plus Social and Behavioral Change Communication Approaches to Improve Food Security: Findings From Formative Research With Syrian Refugees in Lebanon
por: Nassour, Sahar, et al.
Publicado: (2021)

The correlation of HCV RNA and HCV core antigen in different genotypes of HCV
por: Xiang, Yu, et al.
Publicado: (2018)

HCV antigen instead of RNA testing to diagnose acute HCV in patients treated in the Dutch Acute HCV in HIV Study
por: Hullegie, Sebastiaan J., et al.
Publicado: (2017)

People who use drugs in rehabilitation, from chaos to discipline: Advantages and pitfalls: A qualitative study
por: Mahboub, Nadine, et al.
Publicado: (2021)

Key Elements on the Pathway to HCV Elimination: Lessons Learned From the AASLD HCV Special Interest Group 2020
por: Feld, Jordan J., et al.
Publicado: (2021)

Pangenotypic and Genotype-Specific Antivirals in the Treatment of HCV Genotype 4 Infected Patients with HCV Monoinfection and HIV/HCV Coinfection
por: Zarębska-Michaluk, Dorota, et al.
Publicado: (2022)

Performance of 6 HCV genotyping 9G test for HCV genotyping in clinical samples
por: Warkad, Shrikant Dasharath, et al.
Publicado: (2018)

HCV core antigen and HCV-RNA in HIV/HCV co-infected patients with different HCV genotypes
por: Garbuglia, Anna Rosa, et al.
Publicado: (2014)

Flexible and rapid construction of viral chimeras applied to hepatitis C virus
por: McClure, C. Patrick, et al.
Publicado: (2016)

A risk progression breast epithelial 3D culture model reveals Cx43/hsa_circ_0077755/miR-182 as a biomarker axis for heightened risk of breast cancer initiation
por: Naser Al Deen, Nataly, et al.
Publicado: (2021)

Novel HCV Genotype 4d Infectious Systems and Assessment of Direct-Acting Antivirals and Antibody Neutralization
por: Pham, Long V., et al.
Publicado: (2022)

Voices of the vulnerable: Exploring the livelihood strategies, coping mechanisms and their impact on food insecurity, health and access to health care among Syrian refugees in the Beqaa region of Lebanon
por: Nabulsi, Dana, et al.
Publicado: (2020)

Approaches for simplified HCV diagnostic algorithms
por: Fourati, Slim, et al.
Publicado: (2018)

HCV genotyping using statistical classification approach
por: Qiu, Ping, et al.
Publicado: (2009)

Users’ acceptance of electronic patient portals in Lebanon
por: Honein-AbouHaidar, Gladys N., et al.
Publicado: (2020)

Restoration of HCV-Specific Immune Responses with Antiviral Therapy: A Case for DAA Treatment in Acute HCV Infection
por: Casey, Julia L., et al.
Publicado: (2019)

Epidemiological features of patients infected with HCV genotype 4 in Poland: Epidemiology of HCV genotype 4 in Poland
por: Chlabicz, Slawomir, et al.
Publicado: (2011)

Oral lichen planus and HCV infection
por: Tenório, Jefferson R., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_shusl1d3l0sjfdgsgjauh81sba