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Avelumab in Patients With Gestational Trophoblastic Tumors With Resistance to Single-Agent Chemotherapy: Cohort A of the TROPHIMMUN Phase II Trial

PURPOSE: Women with gestational trophoblastic tumors (GTT) resistant to single-agent chemotherapy receive alternative chemotherapy regimens, which, although effective, cause considerable toxicity. All GTT subtypes express programmed death-ligand 1 (PD-L1), and natural killer (NK) cells are involved...

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Detalles Bibliográficos
Autores principales: You, Benoit, Bolze, Pierre-Adrien, Lotz, Jean-Pierre, Massardier, Jérome, Gladieff, Laurence, Joly, Florence, Hajri, Touria, Maucort-Boulch, Delphine, Bin, Sylvie, Rousset, Pascal, Devouassoux-Shisheboran, Mojgan, Roux, Adeline, Alves-Ferreira, Marine, Grazziotin-Soares, Daniele, Langlois-Jacques, Carole, Mercier, Catherine, Villeneuve, Laurent, Freyer, Gilles, Golfier, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499607/
https://www.ncbi.nlm.nih.gov/pubmed/32716740
http://dx.doi.org/10.1200/JCO.20.00803