NGF receptors and PI3K/AKT pathway involved in glucose fluctuation-induced damage to neurons and α-lipoic acid treatment

BACKGROUND: Glucose fluctuation promotes neuronal apoptosis, which plays a central role in diabetic encephalopathy (DE). Nerve growth factor (NGF), and its interaction with high-affinity (TrkA) and low-affinity (p75NTR) receptors, are involved in neuronal survival. NGF/TrkA contributes to the activa...

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Detalles Bibliográficos
Autores principales: Yan, Ting, Zhang, Zhihui, Li, Danqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499848/
https://www.ncbi.nlm.nih.gov/pubmed/32943002
http://dx.doi.org/10.1186/s12868-020-00588-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499848/
https://www.ncbi.nlm.nih.gov/pubmed/32943002
http://dx.doi.org/10.1186/s12868-020-00588-y

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