Cargando…

Genetic profiling of primary and secondary tumors from patients with lung adenocarcinoma and bone metastases reveals targeted therapy options

BACKGROUND: Patients newly diagnosed with lung adenocarcinoma with bone metastases (LABM) have poor survival rates after treatment with conventional therapies. To improve outcomes, we retrospectively investigated whether the application of a more comprehensive genetic test of tumor biopsies samples...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Long, Jiang, Xiao-Liu, Liang, Hong-Bin, Li, Jian-Cheng, Chin, Li-Han, Wei, Jian-Ping, Wang, Rui-Ru, Cai, Jing, Xiong, Qiang, Wang, Lien-Tu, Cram, David S., Liu, An-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499871/ https://www.ncbi.nlm.nih.gov/pubmed/32942985 http://dx.doi.org/10.1186/s10020-020-00197-9

Ejemplares similares

Mandible Bone Metastases Secondary to Pulmonary Adenocarcinoma
por: Dirican¹, Nigar, et al.
Publicado: (2014)

Bone Metastases of Gastrointestinal Stromal Tumor: A Review of Published Literature
por: Yang, Jian, et al.
Publicado: (2020)

PTH1R-CaSR Cross Talk: New Treatment Options for Breast Cancer Osteolytic Bone Metastases
por: Yang, Yanmei, et al.
Publicado: (2018)

Genetic Heterogeneity Between Paired Primary and Brain Metastases in Lung Adenocarcinoma
por: Li, Li, et al.
Publicado: (2020)

Genomic Features of Organ-Specific Metastases in Lung Adenocarcinoma
por: Feng, Alei, et al.
Publicado: (2022)

Icotinib as initial treatment in lung adenocarcinoma patients with brain metastases
por: Xu, Jian‐ping, et al.
Publicado: (2016)

Differential diagnosis and cancer staging of a unique case with multiple nodules in the lung – lung adenocarcinoma, metastasis of colon adenocarcinoma, and colon adenocarcinoma metastasizing to lung adenocarcinoma
por: Bai, Yun, et al.
Publicado: (2015)

Denosumab: a new option in the treatment of bone metastases from urological cancers
por: Yuasa, Takeshi, et al.
Publicado: (2012)

The Incidence of EGFR-Activating Mutations in Bone Metastases of Lung Adenocarcinoma
por: Krawczyk, Paweł, et al.
Publicado: (2013)

Modified Electroconvulsive Therapy in a Patient with Gastric Adenocarcinoma and Metastases to Bone and Liver
por: Wang, Gennie, et al.
Publicado: (2014)

Immunotherapy response and microenvironment provide biomarkers of immunotherapy options for patients with lung adenocarcinoma
por: Zhan, Xue, et al.
Publicado: (2022)

Different long-term oncologic outcomes after radical surgical resection for neuroendocrine carcinoma and adenocarcinoma of the stomach
por: Xie, Jian-Wei, et al.
Publicado: (2017)

A postoperative scoring system for post-hepatectomy early recurrence of colorectal liver metastases
por: Mao, Rui, et al.
Publicado: (2017)

ALK rearrangement in lung adenocarcinoma with concurrent cervix and breast metastases: A case report
por: Chuang, Xin, et al.
Publicado: (2018)

Rechallenge pemetrexed-based chemotherapy provides an option for initially benefited patients with advanced lung adenocarcinoma
por: Wang, Jia-Ni, et al.
Publicado: (2021)

Site-specific metastases of gallbladder adenocarcinoma and their prognostic value for survival: a SEER-based study
por: Yang, Yingnan, et al.
Publicado: (2021)

Relating neurological symptoms to cerebral metastases at the time of initial staging scan
por: Corbally, C, et al.
Publicado: (2015)

Cost of palliative radiation to the bone for patients with bone metastases secondary to breast or prostate cancer
por: Hess, Gregory, et al.
Publicado: (2012)

Cutaneous Metastases from Lung Adenocarcinoma
por: Wang, Yu, et al.
Publicado: (2020)

Hepatoid Adenocarcinoma Of The Lung Metastasizing To The Gingiva
por: Wang, Chunhua, et al.
Publicado: (2019)

Clinical utility of cerebrospinal fluid-derived circular RNAs in lung adenocarcinoma patients with brain metastases
por: Wang, Zhen, et al.
Publicado: (2022)

Restoration of KLF4 Inhibits Invasion and Metastases of Lung Adenocarcinoma through Suppressing MMP2
por: Li, Shaoli, et al.
Publicado: (2017)

Health state utilities for skeletal-related events secondary to bone metastases
por: Matza, Louis S., et al.
Publicado: (2013)

Non-response to preoperative chemotherapy is a contraindication to hepatectomy plus radiofrequency ablation in patients with colorectal liver metastases
por: Mao, Rui, et al.
Publicado: (2017)

Deep learning based automated diagnosis of bone metastases with SPECT thoracic bone images
por: Lin, Qiang, et al.
Publicado: (2021)

Occult olfactory neuroblastoma presenting with multiple bone metastases: a case report
por: Zhou, Qi, et al.
Publicado: (2020)

Two web-based dynamic prediction models for the diagnosis and prognosis of gastric cancer with bone metastases: evidence from the SEER database
por: Liu, Bo, et al.
Publicado: (2023)

Cancer Metastases from Lung Adenocarcinoma Disappeared After Molecular Targeted Therapy: A Successfully Clinical Treatment Experience
por: Li, Meng-Jie, et al.
Publicado: (2022)

Construction and Verification of Nomogram Model for Lung Adenocarcinoma With ≤ 5 Bone-Only Metastases Basing on Hematology Markers
por: Meng, Chunliu, et al.
Publicado: (2022)

Bone metastases in soft tissue sarcoma: a survey of natural history, prognostic value and treatment options
por: Vincenzi, Bruno, et al.
Publicado: (2013)

Exploring the value of new preoperative inflammation prognostic score: white blood cell to hemoglobin for gastric adenocarcinoma patients
por: Zheng, Hua-Long, et al.
Publicado: (2019)

Clinical features and prognostic factors in patients with bone metastases from hepatocellular carcinoma after liver transplantation
por: He, Jian, et al.
Publicado: (2011)

Cerebrospinal fluid circulating tumour DNA genotyping and survival analysis in lung adenocarcinoma with leptomeningeal metastases
por: Bai, Kaixuan, et al.
Publicado: (2023)

Olives and Bone: A Green Osteoporosis Prevention Option
por: Chin, Kok-Yong, et al.
Publicado: (2016)

Are the indications for postoperative radiotherapy in the NCCN guidelines for patients with gastric adenocarcinoma too broad? A study based on the SEER database
por: Huang, Ze-Ning, et al.
Publicado: (2018)

Gene expression profile analysis of the bone microenvironment in patients with spinal metastases
por: Liu, Wangmi, et al.
Publicado: (2018)

Imaging findings of primary pulmonary synovial sarcoma with secondary distant metastases: A case report
por: Li, Rui, et al.
Publicado: (2021)

New Considerations in the Design of Clinical Trials for Bone Metastases
por: Lemke, Madeline, et al.
Publicado: (2012)

Multiple brain metastases in a patient with uterine papillary serous adenocarcinoma: Treatment options for this rarely seen metastatic brain tumor
por: Gulsen, Salih, et al.
Publicado: (2013)

Skeletal standardized uptake values obtained using quantitative SPECT/CT for the detection of bone metastases in patients with lung adenocarcinoma
por: Lin, Lin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_njgc7265iaifouqauerk6qlsba