A novel target enrichment strategy in next-generation sequencing through 7-deaza-dGTP-resistant enzymatic digestion

OBJECTIVE: Owing to the overwhelming dominance of human and commensal microbe sequences, low efficiency is a major concern in clinical viral sequencing using next-generation sequencing. DNA composed of 7-deaza-2′-deoxyguanosine 5′-triphosphate (c(7)dGTP), an analog of deoxyguanosine triphosphate (dG...

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Detalles Bibliográficos
Autores principales: Peng, Peng, Xu, Yanjuan, Di Bisceglie, Adrian M., Fan, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499927/
https://www.ncbi.nlm.nih.gov/pubmed/32948245
http://dx.doi.org/10.1186/s13104-020-05292-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499927/
https://www.ncbi.nlm.nih.gov/pubmed/32948245
http://dx.doi.org/10.1186/s13104-020-05292-y

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