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The compound 2-benzylthio-5,8-dimethoxynaphthalene-1,4-dione leads to apoptotic cell death by increasing the cellular reactive oxygen species levels in Ras-mutated liver cancer cells

The aim of the present study was to verify the pro-apoptotic anticancer potential of several 5,8-dimethoxy-1,4-phthoquinone (DMNQ) derivatives in Ras-mediated tumorigenesis. MTT assays were used to detect cellular viability and flow cytometry was performed to assess intracellular reactive oxygen spe...

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Detalles Bibliográficos
Autores principales:	Shen, Gui-Nan, Li, Jing, Jin, Ying-Hua, Sun, Hu-Nan, Hao, Ying-Ying, Jin, Mei-Hua, Liu, Ren, Li, Wei-Long, Zhang, Yong-Qing, Yu, Jia-Bin, Yu, Nan-Nan, Wang, Wei-Dong, Yu, Li-Yun, Kim, Ji-Su, Kwon, Taeho, Han, Ying-Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500053/ https://www.ncbi.nlm.nih.gov/pubmed/32968439 http://dx.doi.org/10.3892/etm.2020.9209

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