Novel combination therapy for melanoma induces apoptosis via a gap junction positive feedback mechanism

Metastatic melanoma cells overexpressing gap junctions were assayed for their ability to propagate cell death by a novel combination therapy that generates reactive oxygen species (ROS) by both 1) non-thermal plasma (NTP) and 2) tirapazamine (TPZ) under hypoxic conditions. Results demonstrate additi...

Descripción completa

Detalles Bibliográficos
Autores principales: Bagati, Archis, Hutcherson, Timothy C., Koch, Zethan, Pechette, Joseph, Dianat, Hossein, Higley, Cory, Chiu, Lisa, Song, Yesul, Shah, Jay, Chazen, Elana, Nicolais, Andrew, Casey, Peter, Thompson, Kyle, Burke, Kevin, Nikiforov, Mikhail A., Zirnheld, Jennifer, Zucker, Shoshanna N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500108/
https://www.ncbi.nlm.nih.gov/pubmed/32973969
http://dx.doi.org/10.18632/oncotarget.27732

Ejemplares similares

Ejemplares similares