Obeticholic acid improves fetal bile acid profile in a mouse model of gestational hypercholanemia

Intrahepatic cholestasis of pregnancy (ICP) is characterized by elevated maternal circulating bile acid levels and associated dyslipidemia. ICP leads to accumulation of bile acids in the fetal compartment, and the elevated bile acid concentrations are associated with an increased risk of adverse fet...

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Detalles Bibliográficos
Autores principales: Pataia, Vanessa, McIlvride, Saraid, Papacleovoulou, Georgia, Ovadia, Caroline, McDonald, Julie A. K., Wahlström, Annika, Jansen, Eugène, Adorini, Luciano, Shapiro, David, Marchesi, Julian R., Marschall, Hanns-Ulrich, Williamson, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500267/
https://www.ncbi.nlm.nih.gov/pubmed/32597707
http://dx.doi.org/10.1152/ajpgi.00126.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500267/
https://www.ncbi.nlm.nih.gov/pubmed/32597707
http://dx.doi.org/10.1152/ajpgi.00126.2020

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