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Computational biophysical characterization of the SARS-CoV-2 spike protein binding with the ACE2 receptor and implications for infectivity

SARS-CoV-2 is a novel highly virulent pathogen which gains entry to human cells by binding with the cell surface receptor – angiotensin converting enzyme (ACE2). We computationally contrasted the binding interactions between human ACE2 and coronavirus spike protein receptor binding domain (RBD) of t...

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Detalles Bibliográficos
Autores principales: Chowdhury, Ratul, Boorla, Veda Sheersh, Maranas, Costas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500280/
https://www.ncbi.nlm.nih.gov/pubmed/32983400
http://dx.doi.org/10.1016/j.csbj.2020.09.019