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Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca(+2) Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells

Breast cancer is the most heterogenous cancer type among women across the world. Despite concerted efforts, breast cancer management is still unsatisfactory. Interplay between apoptosis and autophagy is an imperative factor in categorizing therapeutics for cancer treatment. Proscillaridin A (PSD-A),...

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Detalles Bibliográficos
Autores principales: Saleem, Muhammad Zubair, Alshwmi, Mohammed, Zhang, He, Din, Syed Riaz Ud, Nisar, Muhammad Azhar, Khan, Muhammad, Alam, Shahid, Alam, Gulzar, Jin, Lingling, Ma, Tonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500466/
https://www.ncbi.nlm.nih.gov/pubmed/33013353
http://dx.doi.org/10.3389/fphar.2020.01055