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Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca(+2) Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells
Breast cancer is the most heterogenous cancer type among women across the world. Despite concerted efforts, breast cancer management is still unsatisfactory. Interplay between apoptosis and autophagy is an imperative factor in categorizing therapeutics for cancer treatment. Proscillaridin A (PSD-A),...
Autores principales: | Saleem, Muhammad Zubair, Alshwmi, Mohammed, Zhang, He, Din, Syed Riaz Ud, Nisar, Muhammad Azhar, Khan, Muhammad, Alam, Shahid, Alam, Gulzar, Jin, Lingling, Ma, Tonghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500466/ https://www.ncbi.nlm.nih.gov/pubmed/33013353 http://dx.doi.org/10.3389/fphar.2020.01055 |
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