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Binding of omeprazole to protein targets identified by monoclonal antibodies

Omeprazole is the most commonly used proton pump inhibitor (PPI), a class of medications whose therapeutic mechanism of action involves formation of a disulfide linkage to cysteine residues in the H+/K+ ATPase pump on gastric secretory cells. Covalent linkage between the sole sulfur group of omepraz...

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Detalles Bibliográficos
Autores principales: Cartee, Naw May Pearl, Wang, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500594/
https://www.ncbi.nlm.nih.gov/pubmed/32946534
http://dx.doi.org/10.1371/journal.pone.0239464

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