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coPLINK: A complementary tool to PLINK
In genome-wide association studies (GWAS), a wide variety of analysis tools have been designed, leading to various formats of GWAS data. How to convert a dataset in non-PLINK format into PLINK format to use its powerful analysis performance, or to convert a dataset in PLINK format into the format of...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500662/ https://www.ncbi.nlm.nih.gov/pubmed/32946477 http://dx.doi.org/10.1371/journal.pone.0239144 |
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author | Liu, Han-Ming Liu, Zhao-Fa Zheng, Jin-Ping Yang, Dan Hu, Sheng-Zhou Yan, Shen-Hai He, Xian-Wen |
author_facet | Liu, Han-Ming Liu, Zhao-Fa Zheng, Jin-Ping Yang, Dan Hu, Sheng-Zhou Yan, Shen-Hai He, Xian-Wen |
author_sort | Liu, Han-Ming |
collection | PubMed |
description | In genome-wide association studies (GWAS), a wide variety of analysis tools have been designed, leading to various formats of GWAS data. How to convert a dataset in non-PLINK format into PLINK format to use its powerful analysis performance, or to convert a dataset in PLINK format into the format of other analysis tools, is a problem that needs to be faced and solved. To address this issue, we developed a tool called coPLINK, a complementary tool to PLINK, to cooperate with PLINK to implement the conversions of GWAS data formats and to provide some additional functions, such as data files comparison. The tool can implement mutual conversions not only between an existing data format and PLINK PED/BED, but also between a user-defined data format and PLINK PED. The usage and performance of the tool are similar to PLINK. The characteristics of the conversions of existing data formats and user-defined formats make it be a good assistant to PLINK or other tools and, have good potential for GWAS studies or other works. |
format | Online Article Text |
id | pubmed-7500662 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-75006622020-09-24 coPLINK: A complementary tool to PLINK Liu, Han-Ming Liu, Zhao-Fa Zheng, Jin-Ping Yang, Dan Hu, Sheng-Zhou Yan, Shen-Hai He, Xian-Wen PLoS One Research Article In genome-wide association studies (GWAS), a wide variety of analysis tools have been designed, leading to various formats of GWAS data. How to convert a dataset in non-PLINK format into PLINK format to use its powerful analysis performance, or to convert a dataset in PLINK format into the format of other analysis tools, is a problem that needs to be faced and solved. To address this issue, we developed a tool called coPLINK, a complementary tool to PLINK, to cooperate with PLINK to implement the conversions of GWAS data formats and to provide some additional functions, such as data files comparison. The tool can implement mutual conversions not only between an existing data format and PLINK PED/BED, but also between a user-defined data format and PLINK PED. The usage and performance of the tool are similar to PLINK. The characteristics of the conversions of existing data formats and user-defined formats make it be a good assistant to PLINK or other tools and, have good potential for GWAS studies or other works. Public Library of Science 2020-09-18 /pmc/articles/PMC7500662/ /pubmed/32946477 http://dx.doi.org/10.1371/journal.pone.0239144 Text en © 2020 Liu et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Liu, Han-Ming Liu, Zhao-Fa Zheng, Jin-Ping Yang, Dan Hu, Sheng-Zhou Yan, Shen-Hai He, Xian-Wen coPLINK: A complementary tool to PLINK |
title | coPLINK: A complementary tool to PLINK |
title_full | coPLINK: A complementary tool to PLINK |
title_fullStr | coPLINK: A complementary tool to PLINK |
title_full_unstemmed | coPLINK: A complementary tool to PLINK |
title_short | coPLINK: A complementary tool to PLINK |
title_sort | coplink: a complementary tool to plink |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500662/ https://www.ncbi.nlm.nih.gov/pubmed/32946477 http://dx.doi.org/10.1371/journal.pone.0239144 |
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