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coPLINK: A complementary tool to PLINK

In genome-wide association studies (GWAS), a wide variety of analysis tools have been designed, leading to various formats of GWAS data. How to convert a dataset in non-PLINK format into PLINK format to use its powerful analysis performance, or to convert a dataset in PLINK format into the format of...

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Detalles Bibliográficos
Autores principales: Liu, Han-Ming, Liu, Zhao-Fa, Zheng, Jin-Ping, Yang, Dan, Hu, Sheng-Zhou, Yan, Shen-Hai, He, Xian-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500662/
https://www.ncbi.nlm.nih.gov/pubmed/32946477
http://dx.doi.org/10.1371/journal.pone.0239144
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author Liu, Han-Ming
Liu, Zhao-Fa
Zheng, Jin-Ping
Yang, Dan
Hu, Sheng-Zhou
Yan, Shen-Hai
He, Xian-Wen
author_facet Liu, Han-Ming
Liu, Zhao-Fa
Zheng, Jin-Ping
Yang, Dan
Hu, Sheng-Zhou
Yan, Shen-Hai
He, Xian-Wen
author_sort Liu, Han-Ming
collection PubMed
description In genome-wide association studies (GWAS), a wide variety of analysis tools have been designed, leading to various formats of GWAS data. How to convert a dataset in non-PLINK format into PLINK format to use its powerful analysis performance, or to convert a dataset in PLINK format into the format of other analysis tools, is a problem that needs to be faced and solved. To address this issue, we developed a tool called coPLINK, a complementary tool to PLINK, to cooperate with PLINK to implement the conversions of GWAS data formats and to provide some additional functions, such as data files comparison. The tool can implement mutual conversions not only between an existing data format and PLINK PED/BED, but also between a user-defined data format and PLINK PED. The usage and performance of the tool are similar to PLINK. The characteristics of the conversions of existing data formats and user-defined formats make it be a good assistant to PLINK or other tools and, have good potential for GWAS studies or other works.
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spelling pubmed-75006622020-09-24 coPLINK: A complementary tool to PLINK Liu, Han-Ming Liu, Zhao-Fa Zheng, Jin-Ping Yang, Dan Hu, Sheng-Zhou Yan, Shen-Hai He, Xian-Wen PLoS One Research Article In genome-wide association studies (GWAS), a wide variety of analysis tools have been designed, leading to various formats of GWAS data. How to convert a dataset in non-PLINK format into PLINK format to use its powerful analysis performance, or to convert a dataset in PLINK format into the format of other analysis tools, is a problem that needs to be faced and solved. To address this issue, we developed a tool called coPLINK, a complementary tool to PLINK, to cooperate with PLINK to implement the conversions of GWAS data formats and to provide some additional functions, such as data files comparison. The tool can implement mutual conversions not only between an existing data format and PLINK PED/BED, but also between a user-defined data format and PLINK PED. The usage and performance of the tool are similar to PLINK. The characteristics of the conversions of existing data formats and user-defined formats make it be a good assistant to PLINK or other tools and, have good potential for GWAS studies or other works. Public Library of Science 2020-09-18 /pmc/articles/PMC7500662/ /pubmed/32946477 http://dx.doi.org/10.1371/journal.pone.0239144 Text en © 2020 Liu et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Liu, Han-Ming
Liu, Zhao-Fa
Zheng, Jin-Ping
Yang, Dan
Hu, Sheng-Zhou
Yan, Shen-Hai
He, Xian-Wen
coPLINK: A complementary tool to PLINK
title coPLINK: A complementary tool to PLINK
title_full coPLINK: A complementary tool to PLINK
title_fullStr coPLINK: A complementary tool to PLINK
title_full_unstemmed coPLINK: A complementary tool to PLINK
title_short coPLINK: A complementary tool to PLINK
title_sort coplink: a complementary tool to plink
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500662/
https://www.ncbi.nlm.nih.gov/pubmed/32946477
http://dx.doi.org/10.1371/journal.pone.0239144
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