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Leiomodin creates a leaky cap at the pointed end of actin-thin filaments
Improper lengths of actin-thin filaments are associated with altered contractile activity and lethal myopathies. Leiomodin, a member of the tropomodulin family of proteins, is critical in thin filament assembly and maintenance; however, its role is under dispute. Using nuclear magnetic resonance dat...
Autores principales: | Tolkatchev, Dmitri, Smith, Garry E., Schultz, Lauren E., Colpan, Mert, Helms, Gregory L., Cort, John R., Gregorio, Carol C., Kostyukova, Alla S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500696/ https://www.ncbi.nlm.nih.gov/pubmed/32898131 http://dx.doi.org/10.1371/journal.pbio.3000848 |
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