Tumors of Atypical Carcinoma of the Parotid Gland and Papillary Thyroid Carcinoma: A Case Report

Lymphoepithelial carcinoma (LEC) is a variant of anaplastic carcinoma usually found in the nasopharynx. It is a rare, aggressive malignant tumor in the salivary glands, which is usually associated with Epstein-Barr virus (EBV), and often presents with facial nerve paralysis when in the parotid gland...

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Autores principales: Kerns, Aileen, Ross, Andrew, Sugihara, Eric M, Bathula, Samba Siva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Otolaryngology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500745/
https://www.ncbi.nlm.nih.gov/pubmed/32963922
http://dx.doi.org/10.7759/cureus.10496
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author Kerns, Aileen
Ross, Andrew
Sugihara, Eric M
Bathula, Samba Siva
author_facet Kerns, Aileen
Ross, Andrew
Sugihara, Eric M
Bathula, Samba Siva
author_sort Kerns, Aileen
collection PubMed
description Lymphoepithelial carcinoma (LEC) is a variant of anaplastic carcinoma usually found in the nasopharynx. It is a rare, aggressive malignant tumor in the salivary glands, which is usually associated with Epstein-Barr virus (EBV), and often presents with facial nerve paralysis when in the parotid gland. This case report is unique in that our patient had EBV-negative LEC, with facial nerve involvement and a concurrent primary papillary thyroid carcinoma (PTC). We successfully managed this patient with surgery and adjuvant chemoradiotherapy. The patient has responded well to the treatment and she showed no evidence of disease at the 24-month follow-up.
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spelling pubmed-75007452020-09-21 Tumors of Atypical Carcinoma of the Parotid Gland and Papillary Thyroid Carcinoma: A Case Report Kerns, Aileen Ross, Andrew Sugihara, Eric M Bathula, Samba Siva Cureus Otolaryngology Lymphoepithelial carcinoma (LEC) is a variant of anaplastic carcinoma usually found in the nasopharynx. It is a rare, aggressive malignant tumor in the salivary glands, which is usually associated with Epstein-Barr virus (EBV), and often presents with facial nerve paralysis when in the parotid gland. This case report is unique in that our patient had EBV-negative LEC, with facial nerve involvement and a concurrent primary papillary thyroid carcinoma (PTC). We successfully managed this patient with surgery and adjuvant chemoradiotherapy. The patient has responded well to the treatment and she showed no evidence of disease at the 24-month follow-up. Cureus 2020-09-16 /pmc/articles/PMC7500745/ /pubmed/32963922 http://dx.doi.org/10.7759/cureus.10496 Text en Copyright © 2020, Kerns et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Otolaryngology
Kerns, Aileen
Ross, Andrew
Sugihara, Eric M
Bathula, Samba Siva
Tumors of Atypical Carcinoma of the Parotid Gland and Papillary Thyroid Carcinoma: A Case Report
title Tumors of Atypical Carcinoma of the Parotid Gland and Papillary Thyroid Carcinoma: A Case Report
title_full Tumors of Atypical Carcinoma of the Parotid Gland and Papillary Thyroid Carcinoma: A Case Report
title_fullStr Tumors of Atypical Carcinoma of the Parotid Gland and Papillary Thyroid Carcinoma: A Case Report
title_full_unstemmed Tumors of Atypical Carcinoma of the Parotid Gland and Papillary Thyroid Carcinoma: A Case Report
title_short Tumors of Atypical Carcinoma of the Parotid Gland and Papillary Thyroid Carcinoma: A Case Report
title_sort tumors of atypical carcinoma of the parotid gland and papillary thyroid carcinoma: a case report
topic Otolaryngology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500745/
https://www.ncbi.nlm.nih.gov/pubmed/32963922
http://dx.doi.org/10.7759/cureus.10496
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AT bathulasambasiva tumorsofatypicalcarcinomaoftheparotidglandandpapillarythyroidcarcinomaacasereport

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